Abstract:

Objective: To investigate the tendency of bacterial distribution and drug resistance of common pathogen in this hospital.
Methods: The VITEK2 Compact system was used to identify main pathogenic bacteria isolated from specimens of infected patients
from August 2012 to July 2013 and the drug sensitivity test was done. Results: 659 strains of pathogenic bacteria were isolated,
including 393 strains of gram-negative bacteria, accounting for 59.64%, 128 strains of gram-positive bacteria, accounting for 19.42%
and 138 strains of fungi, accounting for 20.94%. The drug resistance rates of E.coli to ampicillin, gentamicin, cefepime, ceftriaxone,
aztreonam, selectrin and tetracycline, Klebsiella pneumoniae to ampicillin, piperacillin, and nitrofurantoin, Pseudominas aeruginosa to ampicillin, tetracycline, ceftriaxone and cefazolin, Staphylococcus aureus to penicillin, Staphylococcus epidermidis to selectrin and
penicillin etc, increased gradually. Conclusion: Gram-negative bacteria are mainly E.coli and Gram-positive bacteria are mainly
Staphylococcus epidermis. Keeping track of the changes of the bacteria and keeping their resistance under continuous surveillance are effective ways to give guidance to the rational use of clinical antibacterial drugs.

Key words: pathogen distribution, isolation and culture, drug sensitivity test