Abstract:

Objective: To understand the current infection status of virus hepatitis B（HBV）and the inoculation status of hepatitis B
vaccines among the population of Dali city. To evaluate the effect of immunization with hepatitis B vaccine after the implementation of
children planning immunization strategies. Thereby to provided scientific basis for relevant government department to make strategies
to prevent and control hepatitis B effectively. Methods: 2 130 people who conducted medical examination at Center for Disease
Control and Prevention of Dali City were selected to survey their inoculation status of hepatitis B vaccines. Serological markers of HBV
were inspected by ELISA. Results: The rate of HBsAg positive, HBsAb, HBcAb is 3.29%, 63.80%, 5.63% respectively, and people
with serological markers of HBV overcast percent in total inspection people are 27.37%（583/2 130）, the HBsAg positive rate of
children under the age of 11 groups is obviously lower than that of adult above 22 years old groups. Dali citizens' hepatitis B
vaccination rates is 59.43% on average, while the inoculation rate of children younger than 11 years old groups（96.38%）is clearly
higher than the adult above 22 years old group（21.43%）. The inoculation rates of male are 10.02% higher than female, but the
positive rate of HBsAg of male is 1.81% higher than females. Conclusion: Since adding hepatitis B vaccine into children's
immunization program, inoculating hepatitis B vaccines in large-scale becomes the most effective way to reduce the HBsAg incidence
rate and control HBV infection rate and HBV infection. It is recommanded that the government departments should increase adults
inoculation，as well as strengthen immunization program.

Key words: hepatitis B vaccine, hepatitis B virus, HBV infection rate