In order to enhance the recovery of heavy oil, we carry out in-door experiment and numerical simulation of steam-air flooding. In-door experiment with different mass ratios of air and steam revealed that heavy oil recovery increased first then decreased as the mass ratio of air and steam increased. When the mass ratio of air and steam was 2:32, the oil recovery was the highest, which was up to 68.67%, and temperature at the end of the sand packed tube was almost the same as it was with steam flooding. When the mass ratio of air and steam exceeded 3:32, the oil recovery of steam-air flooding was less than that of steam flooding, and the temperature at the end of the sand packed tube was much lower than that with steam flooding. Numerical simulation of X Block in Liaohe Oilfield by CMG produced similar results as in in-door experiment, although there existed differences in the results due to differences between in-door experiment and the oil field simulation. Through the field pilot in X Block of Liaohe Oilfield, we found that when the mass ratio of air and steam is 1:16.1, oil production rate increased while the water cut decreased with steam-air flooding which proves the accuracy of the in-door experiment and numerical simulation results.