Abstract:

〔Abstract〕 Objective：To study the biomineralization effect of Geranium strictipes anti-caries toothpaste on the enamel caries of bovine incisors. Methods：The ethyl acetate part and n-butanol part of G. strictipes extract were added into the toothpaste matrix to prepare the medicinal toothpaste of G. strictipes. The minimum inhibitory concentration （MIC） of the toothpaste against cariogenic bacteria was determined. The MIC value was used as the experimental concentration to measure the microhardness values before and after demineralization and after remineralization， and the recovery rate of microhardness of enamel surface was calculated. Scanning electron microscope was used to observe the surface morphology of bovine incisors. Results：The recovery rate of surface microhardness of the ethyl acetate fraction group and the n-butanol fraction group were （97±45.61） % and （87±40.45） %， respectively， which were significantly different from those of the deionized water group（P<0.05）. Scanning electron microscope observation showed that the enamel treated by the diluted solution of G. strictipes anti-caries toothpaste had a smooth and compact structure， with no obvious cavity on the surface， but there was a small amount of sediment. Conclusion：The G. strictipes anti-caries toothpaste can inhibit the growth of main oral cariogenic bacteria and has obvious biomineralization effect on the enamel caries of bovine incisors.

Key words:

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