Evaluation Value of NLR in the Diagnosis and Prognosis of Sepsis

Abstract

Abstract:

〔Abstract〕 Objective： To investigate the value of neutrophil-lymphocyte ratio（NLR） in the diagnosis and prognosis of sepsis.Methods： The general and laboratory data of 50 physical examiners（healthy control group）， 50 non-septic patients（case control group） and 78 sepsis patients（sepsis group） were collected in the First Affiliated Hospital of Dali University. To evaluate the diagnostic value and prognostic value of NLR for sepsis， the correlation between NLR and sequential organ failure assessment （SOFA） score and procalcitonin（PCT） was analyzed， and the best prediction threshold of NLR for 28-day mortality rate and patient prognostic risk factors in the patients with sepsis were screened. Results： The NLR level in the sepsis group was significantly higher than that in the healthy control group and the case control group， and the NLR level of the dead patients was significantly higher than that of the surviving patients in the sepsis group， and the differences were statistically significant（P<0.01）. The area of NLR under ROC curve for diagnosis and prognosis of sepsis was 0.81 and 0.75， respectively， and was positively correlated with SOFA score and PCT（P<0.001）. The 28-day mortality rate of sepsis patients with NLR≥9.00 was significantly higher（P<0.001）. The OR value of NLR in the multiple Logistic regression analysis was 1.128， and the OR value was still greater than 1 after adjustment for confounding factors. Conclusion：NLR has a good diagnostic efficacy for sepsis and has a certain value in predicting the 28-day mortality rate of patients.

Key words:

"> font-size:10.5pt, ">neutrophil-lymphocyte ratio, sepsis, sequential organ failure assessment score

CLC Number:

Cheng Mingjing, Li Fuxing, Wang Li, Fan Yujuan, Xiao Min, Xiong Miaomiao, Zhao Weidong.

Evaluation Value of NLR in the Diagnosis and Prognosis of Sepsis [J]. Journal of Dali University, 2022, 7(10): 94-100.

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