Correlation Analysis of Hyperthyroidism and Bone Mineral Density in Postmenopausal Women

Abstract

Abstract:

Objective： To explore the correlation between hyperthyroidism and bone mineral density（BMD） in postmenopausal women. Methods： A total of 220 postmenopausal women who visited the First People's Hospital of Yunnan Province from October 2021 to April 2022 were selected as the study subjects. BMD and thyroid function indicators were compared among all participants. The patients with hyperthyroidism were divided into different subgroups according to the duration of the disease， and BMD measurements were compared among the subgroups. Results： The BMD values of lumbar vertebra， neck of femur， Wards triangle， greater trochanter and the whole body in patients with hyperthyroidism were significantly lower than in those without hyperthyroidism. Among patients with hyperthyroidism， those with a disease duration of ≥1 year had significantly lower BMD values in the lumbar spine compared to those with a disease duration of <1 year（P<0.05）. The levels of free triiodothyronine（FT3） were negatively correlated with BMD values in the neck of femur， Wards triangle， and the whole body， while the levels of free thyroxine（FT4） were negatively correlated with BMD values in Wards triangle. Conclusion： The BMD values of postmenopausal women with hyperthy-roidism are significantly lower than those without hyperthyroidism. Prolonged disease duration is more likely to lead to a decrease in lumbar spine BMD. FT3 and FT4 levels are negatively correlated with BMD values.

Key words:

bone mineral density, thyroid hormone, hyperthyroidism, postmenopausal women, correlation

CLC Number:

R965.2 ','1');return false;" target="_blank">
R965.2

Li Ye, Yu Yanfang, Chen Bin, Su Heng.

Correlation Analysis of Hyperthyroidism and Bone Mineral Density in Postmenopausal Women [J]. Journal of Dali University, 2023, 8(10): 85-89.

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