Journal of Dali University ›› 2023, Vol. 8 ›› Issue (8): 6-10.

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Study on Chemical Constituents of Gentiana nanobella

Ling Haowei1,2, Li Jing1,2, Shi Kaixuan1,2, Liu Rong1,2, Xiao Chaojiang1,2, Jiang Bei1,2*   

  1. (1. Yunnan Key Laboratory of Screening and Research on Anti-Pathogenic Plant Resources from Western Yunnan, Dali, Yunnan 671000, China; 2. College of Pharmacy, Dali University, Dali, Yunnan 671000, China)

  • Received:2023-01-09 Revised:2023-03-03 Online:2023-08-15 Published:2023-07-11

Abstract: Objective: To study the chemical constituents of the dried whole-plant of Gentiana nanobella. Methods: Silica gel column chromatography and gel permeation chromatography were used to isolate and purify the ethyl acetate fraction of the 75% ethanol extract of the dried whole-plant of G. nanobella. The isolated compounds were identified by physicochemical properties and modern spectroscopic techniques. Results: Eight compounds were isolated from the ethyl acetate fraction of the 75% ethanol extract of the dried whole-plant of G. nanobella and identified as uvaol(1), ursolic acid(2), 1β,2α,3α,24-tetrahydroxyurs-12-en-28-oic acid(3), maslinic acid(4), uncargenin C(5), 2α,3α,24-trihydrxyolean-12-en-28-oic acid(6), daucosterol(7), and (7'Z,10'Z,13'Z)-hexadecatrienoic acid monoglyceride(8). Conclusion: All the compounds were isolated from G. nanobella for the first time, among which uncargenin C(5) and (7'Z,10'Z,13'Z)-hexadecatrienoic acid monoglyceride(8) were first isolated from genus Gentiana.

Key words: font-family:Times New Roman, ">Gentiana nanobellafont-family:Times New Roman, ">;font-family:Times New Roman, "> chemical constituentsfont-family:Times New Roman, ">;font-family:Times New Roman, "> extraction and separationfont-family:Times New Roman, ">;font-family:Times New Roman, "> triterpenoids

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