J4 ›› 2010, Vol. 9 ›› Issue (2): 22-23.

• 临床医学 • 上一篇    下一篇

急性胰腺炎动脉血气分析及电解质检测的临床意义

  

  1. 大理学院附属医院消化内科,云南大理 671000
  • 收稿日期:2009-11-30 出版日期:2010-02-15 发布日期:2010-02-15
  • 作者简介:施荣杰,主治医师,主要从事消化内科研究.

The Clinical Significance of Arterial Vigour Analysis and Electrolyte Detection in Acute Pancreatitis

  1. No. 2 Department of Internal Medicine, Affiliated Hospital, Dali University,Dali, Yunnan 671000, China
  • Received:2009-11-30 Online:2010-02-15 Published:2010-02-15

摘要:

目的:观察急性胰腺炎患者动脉血气分析及电解质的变化。方法:将76例急性胰腺炎患者分为轻症组和重症组,分析其
发病48h内采集的动脉血气及电解质的变化。结果:重症组的PaCO2、PaO2、HCO-3明显低于轻症组(P<0.05),pH、K+、Na+及Ca2+两组无统计学差异。在酸碱代谢方面,以呼吸性碱中毒最为常见,其次为呼吸性碱中毒并代谢性酸中毒、代谢性碱中毒、呼吸性酸中毒并代谢性酸中毒。结论:在发生急性呼吸窘迫综合征、多器官功能障碍综合征之前,急性胰腺炎患者已经存在氧代谢、酸碱平衡及电解质紊乱;通过进行动脉血气分析及电解质检测,进行早期干预,对预防多器官功能障碍综合征的发生,降低重症急性胰腺炎病死率具有重要的临床意义。

关键词: 急性胰腺炎, 血气分析, 电解质, 酸碱平衡

Abstract:

Objective: To observe the changes of vigour analysis and electrolyte in acute pancreatitis. Method: The 76 cases of
acute pancreatitis were divided into the mild acute group(MAP)and the severe acute group(SAP), and the changes of artery vigour and electrolyte collected within 48 hours from the patients attacked by the disease were analyzed. Result:The level of PaCO2, HCO3- and PaO2 in the SAP group was obviously lower than that in the MAP group(P<0.05). No statistical difference on the level of pH, K+, Na+ and Ca2+ between the MAP and the SAP groups. In the acid-base metabolism, the respiratory alkalosis is the most common; this was followed by respiratory alkalosis and metabolic acidosis, metabolic alkalosis, respiratory acidosis and metabolic acidosis. Conclusion: In the patients with acute pancreatitis, the oxygen metabolism, acid -base balance and electrolyte disorders have occurred before acute respiratory distress syndrome and multiple organ dysfunction syndrome. Making the detection of electrolyte and arterial vigour analysis, and early intervention are of clinical significance in the prevention of multiple organ dysfunction syndrome and in the reduction of the case fatality rate of acute pancreatitis.

Key words: acute pancreatitis, vigour analysis, electrolyte, acid-base balance

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