J4 ›› 2011, Vol. 10 ›› Issue (8): 50-51.

• 临床医学 • 上一篇    下一篇

拉氧头孢钠治疗细菌性脑膜炎的临床体会

  

  1. 大理学院附属医院,云南大理 671000
  • 收稿日期:2011-06-30 出版日期:2011-08-15 发布日期:2011-08-15
  • 作者简介:谷祥富,主管药师,主要从事医院临床药学研究.

Clinical Experience of Bacterial Meningitis Treated by Latamoxef Sodium

  1. Affiliated Hospital of Dali University, Dali, Yunnan 671000, China
  • Received:2011-06-30 Online:2011-08-15 Published:2011-08-15

摘要:

目的:观察拉氧头孢钠治疗细菌性脑膜炎的临床疗效和安全性。方法:回顾性调查分析近5 年我院治疗细菌性脑膜炎的
病历,随即抽取拉氧头孢钠50mg/kg 治疗组20 例(A 组)和头孢吡肟50 mg/kg 对照组20 例(B 组),1 次/12 h,疗程均为5~14 d。比较两组临床疗效、细菌学改变及不良反应情况。结果:A、月两组的临床痊愈率分别为90.00%、85.00%,A、月两组的临床有效率分别为95.00%、90.00%,二者比较差异无统计学意义(P>0.05)。结论:拉氧头孢钠治疗细菌性脑膜炎的疗效满意,不良反应少,药物安全性高,在新农合和城镇医保范围,可对医疗机构及患者取得双赢,值得在临床推广应用。

关键词: 拉氧头孢钠, 头孢吡肟, 细菌性脑膜炎

Abstract:

Objective: To observe the clinical efficacy and safety of bacterial meningitis treated by latamoxef sodium. Methods:
Retrospective investigation to the bacterial mengitis cases in our hospital in the past 5 years was taken. Forty cases were randomly selected and divided into the latamoxef sodium 50 mg/kg treatment group(group A)and the cefepime 50 mg/kg control group(group B), each with 20 cases. Then the clinical efficacy, bacteriological changes and adverse reactions were compared between the two groups. Results: The clinical efficacy of group A and B was 95.00% and 90.00% respectively, without significant difference (P>0.05). Conclusion: Latamoxef sodium treating bacterial meningitis, which had higher efficacy, safety and less adverse reaction, could reach a win-win situation for both the medical institutions and the patients under the system of new rural cooperative medicare scheme and urban health insurance. It is wealthy of clinical application.

Key words: latamoxef sodium, cefepime, bacterial menigitis

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