LEEP及微波治疗Ⅲ°宫颈糜烂疗效比较

J4 ›› 2011, Vol. 10 ›› Issue (8): 57-59.

LEEP及微波治疗Ⅲ°宫颈糜烂疗效比较

大理学院昆明附属医院，昆明 650011

收稿日期:2011-05-20 出版日期:2011-08-15 发布日期:2011-08-15
作者简介:王永梅，副主任医师，主要从事妇产科研究.

Comparison of LEEP and Microwave Therapy in Class III Cervical Erosion Treatment

Kunming Affiliated Hospital of Dali University, Kunming 650011，China

Received:2011-05-20 Online:2011-08-15 Published:2011-08-15

摘要/Abstract

摘要：

目的：探讨宫颈环形电切术（LEEP）及微波治疗芋毅宫颈糜烂的临床效果。方法：选择Ⅲ°宫颈糜烂患者120例，随机将其
分为两组，治疗组采用LEEP治疗；对照组采用传统的微波治疗，每组各60例。评定两组患者术中出血量、术后15 d脱痂止血及治疗后60 d治愈、好转和无效情况，治疗后90 dHPV 高危型持续感染率。结果：LEEP60 例（其中HPV 感染20 例），术后15 d脱痂止血2 例，术后60、90 d复查，60 例宫颈创面100%愈合（愈合率100%）；术后90 d复查HPV 高危型持续感染2 例（10%），对照组60 例（其中HPV感染18 例），术后15 d脱痂止血12 例，术后60 d复查，宫颈创面完全愈合42 人（愈合率70%），18 例创面愈合1/3~1/2，4 例完全未愈合；术后90 d复查，HPV高危型持续感染6 例（30%）。两组比较差异具有统计学意义（P<0.05）。结论：LEEP治疗宫颈芋毅糜烂，具有创面愈合时间短，HPV 持续感染率低的优点，其疗效优于传统微波治疗。故重度宫颈糜烂可首选LEEP 治疗。

关键词: 宫颈环型电切术, 宫颈芋毅糜烂, 微波治疗

Abstract:

Objective：To investigate the clinical results of cervical LEEP（loop electrosurgical excisional procedure）and microwave therapy in treatment of class III cervical erosion. Methods：One hundred and twenty patients with class III cervical erosion were randomly divided into treatment group（LEEP therapy）and control group（traditional microwave therapy），with 60 cases in each group. Blood loss，effects on exuvial hemorrhage at 15 days and 60 days postoperative，as well as the rate of high-risk HPV infection at 90days postoperative were evaluated. Results：There were 20 cases of HPV infection in LEEP group，2 cases of exuvial hemorrhage were observed at 15 d postoperative，all cases of cervical wounds were 100% healed at 60 d and 90 d postoperative （healing rate 100%）；2 cases （10%）showed high-risk HPV persistent infection at 90 d postoperative. There were 18 cases of HPV infection in
control group，12 cases of exuvial hemorrhage were observed at 15 d postoperative，42 cases of cervical wounds were 100% healed at 60 d and 90 d postoperative （healing rate 70%），meanwhile in 18 cases，about 1/3 to 1/2 of wound healed，and 4 patients did not heal at all；6 cases （30%）showed high-risk HPV persistent infection at 90 d postoperative. The data showed that there were statistic significance between the two groups in healing effect and infection rate （P<0.05）. Conclusion：Compared to the microwave therapy，LEEP therapy got better curative effect with shorter healing time and lower HPV persistent infection rates in treatment of class III cervical erosion.

Key words: loop electrosurgical excision procedure（LEEP）, class III cervical erosion, microwave treatment

中图分类号:

R711.32

王永梅, 李娟, 杨一敏, 周彦. LEEP及微波治疗Ⅲ°宫颈糜烂疗效比较[J]. J4, 2011, 10(8): 57-59.

WANG Yong-Mei, LI Juan, YANG Yi-Min, ZHOU Yan. Comparison of LEEP and Microwave Therapy in Class III Cervical Erosion Treatment[J]. J4, 2011, 10(8): 57-59.