J4 ›› 2016, Vol. 15 ›› Issue (2): 1-4.

• 药学 •    下一篇

滇西地区29种药用植物抗氧化活性研究

  

  1. (大理大学药物研究所,云南大理671000)
  • 收稿日期:2015-04-28 出版日期:2016-02-15 发布日期:2016-02-15
  • 作者简介:张小东,硕士研究生,主要从事药理学研究.
  • 基金资助:

    国家自然科学基金资助项目(81460532)

Research on Antioxidant Activity of 29 Herbal Medicines from West Yunnan

  1. (Institute of Materia Medica, Dali University, Dali, Yunnan 671000, China)
  • Received:2015-04-28 Online:2016-02-15 Published:2016-02-15

摘要:

目的:研究滇西地区29种药用植物提取物体外抗氧化活性。方法:将植物样品用75%乙醇和水依次进行提取,采用
DPPH法测定各供试样品清除自由基的能力,以IC50值评价其活性。结果:在29种药用植物样品中,臭灵丹、滇白珠、反瓣老鹳
草、午香草、昆明山海棠、大红袍、朝天罐、肿柄菊、滇黄芩等9种植物相关供试样品具有很好的抗氧化活性,其中反瓣老鹳草地
下部分醇提物活性极好,IC50值仅为(4.1±0.1)μg/mL,好于阳性对照物维生素C。结论:反瓣老鹳草等9种植物显示出较好的抗
氧化活性,具有进一步研究开发潜力与抗氧化药用价值。

关键词: 药用植物, 抗氧化, DPPH, 粗提物

Abstract:

Objective: To evaluate the antioxidant activity of 29 herbal medicines from West Yunnan. Methods: The 29 medicinal
plants were extracted with 75% ethanol and water successively. DPPH assay were used to measure the antioxidant activity in vitro, and
the results were expressed as IC50 values. Results: Nine plants, including Laggera pterodonta, Gaultheria leucocarpa, Geranium
refractum, Anaphalis bulleyana, Tripterygium hypoglaucum, Campylotropis hirtella, Osbeckia opipara, Tithonia diversifolia, and
Scutellaria amoena, had strong antioxidant activity. Among them, the ethanol extract of the underground part of G. refractum showed
significant activity with an IC50 value(4.1±0.1)μg/mL which was better than the IC50 value of positive control-vitamin C. Conclusion:
Nine plants had antioxidant activity and revealed the potential for further study and development with medicinal purpose.

Key words: herbal medicines, antioxidant, DPPH, crude extract

中图分类号: