›› 2018, Vol. 3 ›› Issue (4): 12-16.

• 药学 • 上一篇    下一篇

栽培及野生粗茎秦艽质量研究——兼论秦艽质量标准

  

  1. (大理大学药学与化学学院,云南大理671000)
  • 收稿日期:2017-01-10 修回日期:2018-02-12 出版日期:2018-04-15 发布日期:2018-04-15
  • 通讯作者: 段宝忠,副教授.
  • 作者简介:陶爱恩,硕士研究生,主要从事中药资源与鉴定研究.
  • 基金资助:

    云南省教育厅科学研究基金资助项目(2014Z135);云南省基础研究计划青年项目(2016FD073);云南省中青
    年学术技术带头人后备人才项目(2015HB058);云南省科技计划项目(2012CG019;2014RE016)

A Study of the Quality of Cultivated and Wild Gentiana Crassicaulis ——Concurrently Discussing the Quality Standards of Gentiana Crassicaulis

  1. (College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China)
  • Received:2017-01-10 Revised:2018-02-12 Online:2018-04-15 Published:2018-04-15

摘要:

目的:研究栽培及野生粗茎秦艽性状、组织结构及化学成分差异,为秦艽药材质量标准修订提供参考。方法:采用性状观察、显微特征比较、中药指纹图谱、浸出物和有效成分含量测定等方法,对栽培及野生粗茎秦艽进行比较研究。结果:粗茎秦艽栽培品及野生品性状上有一定差异,而显微结构、化学指纹图谱、浸出物和有效成分含量差异不明显。结论:粗茎秦艽栽培品药材质量较好,但性状特征不符合药典,建议在标准修订时补充完善相关性状特征。

关键词: 粗茎秦艽, 栽培和野生, 质量, 指纹图谱

Abstract:

Objective: To study the differences between cultivated and wild Gentiana Crassicaulis in the aspects of character, tissue structure and chemical composition, and to provide theoretical basis and data for the revision of Gentianae macrophyllae Radix quality standards. Methods: Regular pharmacognosy methods were employed to examine the traits of medicinal parts and characters of microscopic identification. Furthermore, a HPLC method was used for quantitative analysis of bioactive components and chemical fingerprint. Results: The results showed that the differences between the cultivated and the wild Gentiana Crassicaulis were significant, while there were no significant differences between microstructures, chemical fingerprints, ethanol extracts and the content of active ingredients. Conclusion: The cultivated Gentiana Crassicaulis have a good quality, but the characters of traits don't conform to the standard of Pharmacopoeia of People's Republic of China. It's suggested that the standards should be supplemented when revised.

Key words: Gentiana crassicaulis, cultivated and wild, quality, fingerprint

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