大理大学学报 ›› 2019, Vol. 4 ›› Issue (2): 65-.

• 临床医学 • 上一篇    下一篇

大理市肺炎病人中支原体肺炎感染临床特点分析

段芃嫄,李柳琴,宋志忠,王鹏   

  1. (1.昆明医科大学公共卫生学院,昆明650500;2.大理大学大理教学医院检验科,云南大理671000;
    3.云南省疾病预防控制中心,昆明650011;4.云南省地方病防治所云南省自然疫源性疾病防控技术
    重点实验室,云南大理671000)
  • 收稿日期:2018-09-11 修回日期:2018-12-27 出版日期:2019-02-15 发布日期:2019-02-15
  • 通讯作者: 王鹏,副主任技师,E-mail:wp030801@126.com.
  • 作者简介:段芃嫄,硕士研究生,主要从事流行病与卫生统计研究.
  • 基金资助:
    云南省重大科技专项资助项目(2018ZF008)

Investigation of Mycoplasma Pneumoniae Infection in Patients with Pneumonia in Dali

Duan Pengyuan, Li Liuqin, Song Zhizhong, Wang Peng   

  1. (1. College of Public Health, Kunming Medical University, Kunming 650500, China; 2. Clinical Laboratory, Dali Teaching Hospital of
    Dali University, Dali, Yunnan 671000, China; 3. Yunnan Provincial Centers for Disease Control and Prevention,
    Kunming 650011, China; 4. Yunnan Provincial Key Laboratory for Zoonosis Diseases Control and Prevention,
    Yunnan Institute for Endemic Diseases Control and Prevention, Dali, Yunnan 671000, China)
  • Received:2018-09-11 Revised:2018-12-27 Online:2019-02-15 Published:2019-02-15

摘要: [摘要]目的:以实时荧光聚合酶链式反应(qPCR)筛查社区获得性肺炎患者中的支原体肺炎(MPP)病例,并归纳总结MPP在
人口统计学、临床表现、实验室检测和影像学表现的特点。方法:选取大理大学大理教学医院(大理市第一人民医院)2017年8
月至2018年2月间共182例以肺炎收住入院的患者为研究对象,以RepMP1基因设计引物,用qPCR方法检测研究对象的呼吸
道标本,收集182例患者临床资料。结果:共有12例病例诊断为MPP阳性,通过对这些患者的住院信息分析,发现这些患者普
遍存在发热症状,且C反应蛋白较非MPP者更高。结论:qPCR方法可快速检测MPP病例,且MPP患者C反应蛋白相比其他社
区获得性肺炎更高,可为临床诊断和治疗提供一定参考。

关键词: [关键词]肺炎支原体感染, 实时PCR, 临床特点, 大理市

Abstract: 〔Abstract〕Objective: To screen the cases with Mycoplasma pneumoniae pneumonia (MPP)in patients with community-acquired
pneumonia (CAP) by using quantitative real time polymerase chain reaction (qPCR), and to describe clinical, demographic,
laboratory and imaging characteristics of MPP. Methods: A total of 182 patients with CAP who were admitted to Dali Teaching
Hospital of Dali University(the First People's Hospital of Dali)from August 2017 to February 2018 were selected. The respiratory
specimens of above subjects were detected by qPCR according to primers for RepMP1 gene, and the clinical data of those 182 patients
were collected. Results: Positive MPP was detected in 12 cases. By analyzing the clinical data of these patients, we found that the
common symptom of these patients was fever, and their C reactive proteins were higher than non-MPP patients. Conclusion: The
qPCR can be applied to the detection of MPP. In addition, the C reactive proteins of MPP patients are higher than non-MPP patients,
which can provide some references for clinical diagnosis and treatment.

Key words: 〔Key words〕mycoplasma pneumoniae infection, real-time PCR, clinical characteristics, Dali Municipality