J4 ›› 2012, Vol. 11 ›› Issue (6): 20-22.
目的：探讨牛肝菌对小鼠免疫功能的影响。方法：将牛肝菌的水溶液和脂溶液分别灌胃小鼠10 d，检测小鼠免疫器官重量、巨噬细胞吞噬能力、T淋巴细胞增殖情况及细胞因子产生的情况。结果：牛肝菌脂溶组中小鼠的多数指标均高于水溶组；并且牛肝菌对雌性小鼠的免疫增强作用强于雄性小鼠。结论：牛肝菌有增强免疫功能及抗肿瘤的作用。
Objective: To observe the effect of bolete on immune function of mice. Methods: Intragastric administration of bolete in aqueous solution or in lipid solution into the mice for 10 days consecutively. Organ weight of thymus and spleen, phagocytic capacity of macrophage, proliferation of T lymphocyte and cytokines inducement were investigated. Results: Indexes of lipid solution group were higher compared with that of aqueous group. Bolete manifested obvious effect on immunologic enhancement of female mice compared with the male mice. Conclusion: Bolete could enhance immune function and show anti-tumor effect in mice.
