Abstract:

Objective: To study the curative effect of low molecular heparin calcium in the treatment of acute exacerbation of
chronic pulmonary heart disease. Method: 78 Patients who suffered from the acute exacerbation of chronic pulmonary heart disease were divided into the observation group （40cases）and the control group （38cases）by the random method. The two groups were given routine treatments, such as, oxygen, antiinfection, cough-and-asthma-relieving, improvement of heart and lung function, etc. The observation group was given the routine treatment plus injection under the abdominal skin with 5000 IU low molecular heparin calcium per day for 10 days as a course. Then, the clinical efficacy of the two groups, the blood gas and the hemorheology were observed. Result: The cardio pulmonary function of observation group was improved obviously. When the two groups were compared, it was found that the total effective rate was 90% in the observation group and 71% in the control group, There were significant differences between the two groups（P<0.05）. The observation group has significantly decreased in hematocrit, total blood viscosity, plasma viscosity, fibrinogen and erythrocyte sedimentation; PaCO₂ reduced and PO₂ rose evidently. Conclusion: Low molecular heparin calcium in treatment of acute exacerbation of chronic pulmonary heart disease is safe, effective and worth clinical application.

Key words: low molecular heparin calcium, chronic pulmonary heart disease