Abstract:

Objective: To explore the reasonable and effective preventative measure and therapeutical methods in the treatment of
natrium metabolism turbulence after the operation for pituitary adenomas. Methods: After operation, the natrium metabolism turbulence occurring in the 986 cases of pituitary adenomas from March, 2000 to April, 2005 was reviewed retrospectively to evaluate complications. Results: Hypernatrema occurred in 207 cases （21.0%）, of which 201 suffering from diabetes insipidus syndrome （97.1%）. Hyponatrema occurred in 112 cases （11.4%）, of which 45 suffering from Cerebral Salt Wasting Syndrome （40.2%）. Syndrome of lnappropriate Secretion of Antidiuretic Hormone（SIADH）occurred in 59 cases（52.7%）. Conclusion：On one hand, to reduce the occurrence rate of natrium metabolism turbulence after operation for pituitary adenomas, we must avoid damaging their hypothalamus, hypophysis and blood vessel; on the other hand, for the natrium metabolism turbulence had happened, we must
definitize their diagnosis and take effective therapeutical methods in time. Most of such complications can be cured in a short term.

Key words: pituitaryb adenoma, diabetes insipidus syndrome, hypernatrema, hyponatrema, Cerebral Salt Wasting Syndrome