Chemical Constituents of Holotrichia diomphalia Bates

Abstract

Abstract:

Objective: To investigate the chemical constituents of medicinal insects of Holotrichia diomphalia Bates. Methods:
Various chromatography materials and technology （including silica gel, RP-18 reverse phase silica gel, Sephadex LH-20, MCI gel CHP 20P, D101 macroporous adsorption resin column chromatography and high performance liquid chromatography）, combined with spectroscopic methods （NMR, MS, ORD）were applied to separate and identify the compourds of H. diomphalia Bates. Results: Ten compounds were isolated from H. diomphalia. Their structures were respectively identified as trans-1, 2-cyclohexanediol（1）,（9Z）-glycerin-1-monooleate（2）, salicin（3）, 4-methoxyphenyllacetic acid（4）, glycerin-1-benzoate（5）, yangjinhualine A（6）,（±）-dimerthyl-2（（phenylmethoxy）methoxy）pentanedioate（7）, salicyl alcohol（8）,（p-hydroxyphenyl）acetic acid（9）, and oxiran-2-ylmethanol （10）by a suit of spectroscopic techniques. Conclusion: All the compounds were isolated from H. diomphalia for the first time.

Key words: medicinal insects, Holotrichia diomphalia Bates, chemical constituents, yangjinhualine A

CLC Number:

R284.1

LI Lin, LI Xiao-Nian, WEI Shu-Si, YAN Yong-Meng, ZHONG Hui-Min, CHENG Yong-Xian. Chemical Constituents of Holotrichia diomphalia Bates[J]. J4, 2012, 11(9): 1-4.

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