J4 ›› 2013, Vol. 12 ›› Issue (6): 90-92.

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In Vitro Study of the Effect of Gerbera piloselloides Ethanol Extract on the Uterus of Rat

  

  1. College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China
  • Received:2012-08-30 Revised:2013-04-29 Online:2013-06-15 Published:2013-06-15

Abstract:

Objective: To investigate the effect of ethanol extract from leaves of Gerbera piloselloides on the uterus of rat in vitro.
Methods: Ten mature female but not pregnant SD rats were executed by strike, and uterine horns were used for the rat uterus
segment in vitro. BL-420E+ Biological Functional System was used to record uterine tension, the effect of Gerbera piloselloides
Ethanol Extract on spontaneous contraction and oxytocin-induced contraction of uterus were recorded. Results: The extract could
slow down the uterine contraction frequency and decrease the contraction intensity, and weaken the uterine motility as well.
Conclusion: The ethanol extract of Gerbera piloselloides has significant inhibitive effect on the spontaneous contraction and oxytocininduced
contraction of rat uterus in vitro.

Key words: Gerbera piloselloides, ethanol extract, rat, uterus in vitro

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