Effect of Total Extracts from Mirabilis jalapa on the Contraction Activity of Isolated Rat Uterine Smooth Muscle

doi:10. 3969/j. issn. 1672-2345. 2

Abstract

Abstract:

Objective: To observe the effects of total extracts from Mirabilis jalapa on the spontaneous contraction and induced
contraction by oxytocin of isolated uterine smooth muscle of rat. Methods: The isolated uterine specimen was prepared from killed rats. Constriction action was recorded by the biological function system. The effect of total extracts from Mirabilis jalapa on spontaneous contraction and induced contraction on isolated rat uterine smooth muscle was analyzed. Results: The extracts from Mirabilis jalapa could inhibit the spontaneous contraction and induced contraction by oxytocin, in less contraction frequency and eased contraction tension. Conclusion: The extracts from Mirabilis jalapa have an apparently inhibitory effect on the spontaneous contraction and induced contraction by oxytocin on the isolated rat uterine smooth muscle.

Key words: total extract of Mirabilis jalapa, isolated uterine smooth muscle, spontaneous contraction, induced contraction

CLC Number:

R285.5

LI Cheng-Yao, CHENG Sheng-Bang, LUO Ai-Lian, WANG Yan-Shuang, GUO Mei-Xian. Effect of Total Extracts from Mirabilis jalapa on the Contraction Activity of Isolated Rat Uterine Smooth Muscle[J]. J4, 2013, 12(9): 7-10.

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