J4 ›› 2014, Vol. 13 ›› Issue (8): 1-3.

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Chemical Constituents of Stellera chamaejasme

  

  1. 1.College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China; 2. State Key Laboratory of Phytochemistry and Plant Resources Sustainable Utilization in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201,China;3. School of Pharmacy, Yunnan University of Traditional Chinese Medicine, Kunming 650500, China
  • Received:2014-04-21 Online:2014-08-15 Published:2014-08-15

Abstract:

Objective: To research the chemical constituents of Stellera chamaejasme. Methods: The constituents were isolated from the plant by silica gel column chromatography, C18 reversed phase chromatography, Sephadex LH-20 gel filtration chromatography and HPLC. Their structures were elucidated by spectroscopic methods. Results: Five known compounds were isolated and identified as (2R, 3S)- 3- (3, 4- dimethoxybenzyl)- 2- (3, 4- methylenedioxybenzyl)- butyrolactone (1), haplomyrfolin (2), dihydrosesamin (3), isoneochamaejasmine A (4) and ruixianglangdusu B (5), respectively. Conclusion: Compounds 1-3 were isolated from this plant for the first time.

Key words: Stellera chamaejasme, thymelaeaceae, chemical constituents

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