Abstract:

Objective: To understand the utilization of cephalosporins in the pediatric outpatient department in hospital and to
promote the rational use of cephalosporins. Methods: By the retrospective investigation and analysis method, 1 800 prescriptions of
antibiotics from January to March 2014 were randomly selected and the application data of cephalosporins was analyzed including
varieties, the case number, use frequency and diagnosis and drug combination. Results: Antimicrobial use rate was 62.36%. Of the
total 1 800 prescriptions, 1 007 were prescriptions of cephalosporins（55.94%）. The largest number of cephalosporins used in cases was the first generation cephalosporin cefazolin sodium. Cephalosporins by intravenous drip accounted for 46.22% of the total antibiotic prescriptions and oral cephalosporins accounted for 9.72% . Prescriptions of a single antibiotic accounted for 79.44% ,prescriptions of combined use of two antibiotics accounted for 20.50% and prescriptions of combined use of three antibiotics accounted for 0.06%. Conclusion: The use of cephalosporins in pediatric outpatient department was basically reasonable, while unreasonable phenomena existed in dosing method, administration route, solvent selection and compatibility etc. It is suggested that physicians should strengthen their learning, pharmacists intervene timely and functional departments strengthen supervision.

Key words: antibiotics, cephalosporins, pediatric prescriptions, rational drug use