J4 ›› 2016, Vol. 1 ›› Issue (4): 14-16.

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Chemical Constituent of Swertia angustifolia Buch.II

  

  1. (College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China)
  • Received:2015-09-21 Online:2016-04-15 Published:2016-04-15

Abstract:

Objective: To explore the chemical constituents of Swertia angustifolia Buch. Methods: Compounds were separated and
purified by silica gel and Sephadex LH- 20 column chromatography and their structures were elucidated on the basis of
physicochemical properties and spectral analysis. Results: Seven monomeric compounds were obtained from ethyl acetate extract of S.
angustifolia, which were characterized to be vanillic acid(1), 1,3,8-trihydroxy-5-methoxy xanthone(2), 5, 7, 4′-trihydroxy flavanone
(3), 1-Hydroxy-3, 5, 6-trimethoxy xanthone(4), methyl -3, 4-dihydroxy benzoate(5), diisobutyl-phthalate(6), methyl-bellidifolin
(7). Conclusion: All seven compounds were obtained from S. angusifolia for the first time .

Key words: Swertia angustifolia Buch. , chemical constituents, separation study

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