Abstract:

Objective: To observe the clinical effect and adverse reaction of transdermal fentanyl in treating cancer pain. Methods:
126 patients with cancer pain were divided into moderate and severe cancer pain group with the treatment of transdermal fentanyl, and
the sum up the pain relief effects, adverse reactions, quality of life grading in patients received treatment. Results: Pain of those
patients had relived at some degrees. For moderate group, CR is 57.0%; for severe group, CR is 54.5%. The difference is statistical
significant.There was no severe averse events occurred such as dizziness, constipation, nausea, drowsiness and cutaneous pruritus.
Conclusion: Transdermal fentanyl were convenient, effective and with minor averse events in managing cancer pain clinically.

Key words: transdermal fentanyl, treatment, cancer pain