Abstract:

Objective: To understand the differences between whole blood（WB）mode and pre- dilution（PD）mode when using
Sysmex XN1000, the automatic hematology analyzer, to test blood cells. Methods: To compare the precision of two modes in testing
White blood cells（WBC）, red blood cells（RBC）, hemoglobin（Hb）, hematocrit（HCT）, platelets（PLT）. Results: The precision of each
test in whole blood mode corresponded with the requirements of precision in automatic blood analyzer；the precision of each testin predilution
mode exceed the requirements of precision in automatic blood analyzer, t test showed that three group testing results of the two
modes had significant differences in precision（P<0.05）. The precision of PLT is the lowest. Conclusion: The whole blood mode,
instead of the pre-dilution mode,should be adopted to test blood cells. The pre-dilution mode can only be adopted for infants and
patients who are not suitable for venous blood collection.

Key words: Sysmex XN1000 hematology analyzer, whole blood mode, pre-dilution mode, clinical application