›› 2017, Vol. 2 ›› Issue (8): 53-55.
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Abstract:
Objective:To observe effects of Wang-bi detoxification herbal medication on T-lymphocyte subgroups of patients with Rheumatoid Arthritis, and to explore the mechanism of it efficacy. Methods:A comparative study was conducted among 200 patients including inpatients and outpatients who were divided into two groups randomly. 100 patients in the control group took Indometacin Enteric-coated Tablets with 25 mg every time and once a day, and Methotrexate Tablets with 7.5 mg every time and once a week, while 100 patients in the treatment group took Wang-bi detoxification herbal medication with 200 mL each time and twice a day. After two courses of eight weeks, we compared CD4 + and CD8 + of the two groups before and after the treatment. Results:There was no significant difference with regard to the comparison of CD4+ and CD8+ of each group before the treatment(P>0.05). However, after the treatment both of the groups had a lower CD4+ and a higher CD8 and a lower ratio of CD4+ to CD8+. Comparison between the two groups also showed no significant difference(P>0.05). Conclusion:Patients with RA has an autoimmune disorder. Wang- bi detoxification herbal medication can help the distribution of their T-lymphocyte subsets and help them keep a stable immune system, and can have a similar immunosuppressive effect as that produced by the therapy of MTX in combination with other medicines.
Key words: rheumatoid arthritis, Wang-bi detoxification herbal medication, T-lymphocyte subgroups
CLC Number:
R593.22
Tang Zhenli. Effects of Wang-bi Detoxification Herbal Medication on T-lymphocyte Subgroups of Patients with Rheumatoid Arthritis[J]. , 2017, 2(8): 53-55.
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