Abstract:

〔Abstract〕Objective：To observe the curative effect of treating tuberculous cervical lymphadenopathy with ultrasound-mediated
targeted drug delivery. Methods：120 patients with cervical lymph node tuberculosis were randomly divided into three groups with 40
in each group: the treatment group of ultrasound medicines transdermal, the local injection group and the control group. Three groups were
all treated with conventional anti-tuberculosis therapy. The control group was treated with routine anti-tuberculosis chemotherapy and
without partial treatment. The treatment group was given percutaneous thrombin injection of Isoniazid and Amikacin under ultrasound
guidance. The local injection group was injected with Isoniazid and Amikacin. Besides comparing curative effects of the three groups,
we observed the size of lymph node of the experimental group in different time periods. Results: The overall curative effect of the
experimental group was higher than that of the local injection group and the control group, and there was a significant statistic
difference（P<0.05）; the effective rate of the treatment group reached the highest within 28 days, and there were no significant
differences after 21-day and 28-day treatment（P >0.05）. Conclusions：It is a safe and effective way to treat lymph node tuberculosis
with ultrasonic penetration, and the best advisable treatment course is from 21 to 28 days.

Key words: 〔Key Words〕ultrasound, transdermal, lymph node tuberculosis, treatment