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    15 October 2018, Volume 3 Issue 10
    Network Pharmacology-based Study on Mechanism of DangGuiBuXue Decoction in Treating Anemia
    Li Yang, Hao Junjie
    2018, 3(10):  1-6. 
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    〔Abstract〕Objective:To predict the mechanism of DangGuiBuXue decoction in treating anemia by using network pharmacology
    technique. Methods: TDT and TCMSP databases were used to screen the chemical composition of DangGuiBuXue decoction; OMIM
    database screened the targets of anemia; PPI database established the interaction targets between the drug and the disease. Cytoscape
    software was applied to construct the "compound-target-disease" complex network diagram. Targets of DangGuiBuXue decoction were
    selected, which played an important role in treating anemia by using the network topological parameters such as Degree, Betweenness
    Centrality, Closeness Centrality. In the "component-target-disease" network of DangGuiBuXue decoction, the targets which achieved
    the standard were enriched by the DAVID database. Results: 15 targets correlated with anemia were screened. DangGuiBuXue
    decoction was useful for treating anemia