Reliability Analysis of Neonatal Total Bilirubin Level Determined by the Transcutaneous Jaundice Detector

Abstract

Abstract: 〔Abstract〕Objective: To evaluate the correlation and consistency of neonatal total bilirubin（TBIL）determined by transcutaneous
jaundice detector and automatic biochemistry analyzer. Methods: We retrospectively reviewed 383 neonates with hyperbilirubinemia
who were hospitalized in the Department of Neonatology, Longgang District Central Hospital of Shenzhen from June 2017 to June 2019.
According to TBIL values detected by automatic biochemistry analyzer, the patients were divided into the moderate jaundice group with
198 neonates, the severe jaundice group with 120 neonates, and the extremely severe jaundice group with 65 neonates. The TBIL
values were determined simultaneously by transcutaneous jaundice detector and automatic biochemistry analyzer. The correlation and
consistency of TBIL values determined by the two methods were analyzed by Spearman Correlation Coefficient and Bland-Altman
Scatter Plot. Results: The differences of TBIL values of the neonates in all the groups with different degrees of jaundice determined by
the two methods were significant（P＜0.01）. There was a significant positive correlation between TBIL values detected by
transcutaneous jaundice detector and values by automatic biochemistry analyzer（r = 0.973, P＜0.01）, but the consistency of TBIL
values detected by the two instruments was poor. Conclusion: Transcutaneous bilirubin（TCB）is a better tool used to monitor children
with moderate and severe jaundice, but for children with very severe jaundice, TCB alone is not enough and dynamic monitoring of
serum total bilirubin（STB）is also needed.

Key words: 〔Key words〕bilirubin, transcutaneous jaundice detector, automatic biochemistry analyzer, neonates

CLC Number:

R722.17

Huang Xunbin, Cheng Guoqiang, Qiu Huixian. Reliability Analysis of Neonatal Total Bilirubin Level Determined by the Transcutaneous Jaundice Detector[J]. Journal of Dali University, 2021, 6(4): 62-66.

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