Journal of Dali University ›› 2023, Vol. 8 ›› Issue (8): 6-10.

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Study on Chemical Constituents of Gentiana nanobella

Ling Haowei12 Li Jing12 Shi Kaixuan12 Liu Rong12 Xiao Chaojiang12 Jiang Bei12*   

  1. 1. Yunnan Key Laboratory of Screening and Research on Anti-Pathogenic Plant Resources from Western Yunnan Dali Yunnan 671000 China 2. College of Pharmacy Dali University Dali Yunnan 671000 China

  • Received:2023-01-09 Revised:2023-03-03 Online:2023-08-15 Published:2023-07-11

Abstract: Objective To study the chemical constituents of the dried whole-plant of Gentiana nanobella. Methods Silica gel column chromatography and gel permeation chromatography were used to isolate and purify the ethyl acetate fraction of the 75% ethanol extract of the dried whole-plant of G. nanobella. The isolated compounds were identified by physicochemical properties and modern spectroscopic techniques. Results Eight compounds were isolated from the ethyl acetate fraction of the 75% ethanol extract of the dried whole-plant of G. nanobella and identified as uvaol1), ursolic acid2), 1β,2α,3α,24-tetrahydroxyurs-12-en-28-oic acid3), maslinic acid4), uncargenin C5), 2α,3α,24-trihydrxyolean-12-en-28-oic acid6), daucosterol7), and 7'Z10'Z13'Z-hexadecatrienoic acid monoglyceride8. Conclusion All the compounds were isolated from G. nanobella for the first time among which uncargenin C5 and 7'Z10'Z13'Z-hexadecatrienoic acid monoglyceride8 were first isolated from genus Gentiana.

Key words: font-family:Times New Roman, ">Gentiana nanobellafont-family:Times New Roman, ">;font-family:Times New Roman, "> chemical constituentsfont-family:Times New Roman, ">;font-family:Times New Roman, "> extraction and separationfont-family:Times New Roman, ">;font-family:Times New Roman, "> triterpenoids

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