Exploring strategies for English publicity translation in China's international communication from a cross-cultural perspective bears great practical significance. It supports the establishment of cross-cultural interpretative mechanisms, deepens theoretical inquiries into perspective shifts, and enhances national capacity for publicity translation. In response to current challenges, including insufficient research on cross-cultural communication, inadequate audience awareness, misalignment of communication elements, content gaps, and technological limitations, this study proposes strategies such as strengthening translation actors, prioritizing audience orientation, accurately applying the "5W" communication model, enriching content, and upgrading technology. These strategies aim to inform and improve translation practices within the broader context of cross-cultural communication.