Abstract:

Objective: To observe the clinical curative effect of sodium nitroprusside combined with dopamine in the treatment of
acute left heart failure. Methods: Patients with acute left heart failure in 116 cases were randomly divided into the treatment group, the
control group with 58 cases in each group. The treatment group was given sodium nitroprusside combined with dopamine for treatment,
the control group was treated with isosorbide mononitrate therapy. Results: The total efficiency of the treatment group and the control
group were respectively 89.7% and 50%. The treatment group was significantly higher than the control group（P<0.01）. The left
ventricular ejection fraction（LVEF）after treatment was higher than that before the treatment（P<0.05）in both groups, with the
treatment group being significantly increased（P<0.05）. Conclusion: Sodium nitroprusside combined with dopamine is safe and
effective in treating acute left heart failure, isosorbide mononitrate therapy is better than single use.

Key words: sodium nitroprusside, dopamine, acute left heart failure