›› 2017, Vol. 2 ›› Issue (4): 41-45.

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Analysis on Clinical Efficacy of Treating 198 Cases of Acute Cerebral Infarction TOAST Classification of Urokinase Intravenous Thrombolytic Therapy

  

  1. (The Department of Neurology, The Forth Affiliated Hospital of Dali University, Chuxiong, Yunnan 675000, China)
  • Received:2014-09-12 Revised:2017-01-11 Online:2017-04-15 Published:2017-04-15

Abstract:

Objective: To review the effectiveness and safety of acute cerebral infarction TOAST classification with urokinase
intravenous thrombolytic therapy. Methods: The total effective rate of TOAST and the NIHSS before and after thrombolysis in acute
cerebral infarction were compared. Results: LAA, CE, SAO, SOE, SUE and total effective rate were 93.65%, 34.21%, 92.85%,
76.92%, 80.00%, respectively; NIHSS of LAA and SAO before and after thrombolytic therapy showed significant difference(P<0.05);
the comparison of SOE, SUE, CE in the third week after thrombolytic therapy showed significant difference(P<0.05). There was no
significant difference in NIHSS among different subtypes of TOAST before and after thrombolytic therapy(P>0.05). There was
significant difference in total effective rate and bleeding rate between LAA and SAO in different time windows(P<0.05). Conclusion:
The dose of acute cerebral infarction TOAST classification of urokinase thrombolytic therapy should be individualized.

Key words: cerebral infarction, urokinase, intravenous thrombolysis, TOAST classification, dose

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