›› 2017, Vol. 2 ›› Issue (4): 41-45.
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Objective: To review the effectiveness and safety of acute cerebral infarction TOAST classification with urokinase intravenous thrombolytic therapy. Methods: The total effective rate of TOAST and the NIHSS before and after thrombolysis in acute cerebral infarction were compared. Results: LAA, CE, SAO, SOE, SUE and total effective rate were 93.65%, 34.21%, 92.85%, 76.92%, 80.00%, respectively; NIHSS of LAA and SAO before and after thrombolytic therapy showed significant difference(P<0.05); the comparison of SOE, SUE, CE in the third week after thrombolytic therapy showed significant difference(P<0.05). There was no significant difference in NIHSS among different subtypes of TOAST before and after thrombolytic therapy(P>0.05). There was significant difference in total effective rate and bleeding rate between LAA and SAO in different time windows(P<0.05). Conclusion: The dose of acute cerebral infarction TOAST classification of urokinase thrombolytic therapy should be individualized.
Key words: cerebral infarction, urokinase, intravenous thrombolysis, TOAST classification, dose
CLC Number:
R743.3
Li Wenwu. Analysis on Clinical Efficacy of Treating 198 Cases of Acute Cerebral Infarction TOAST Classification of Urokinase Intravenous Thrombolytic Therapy[J]. , 2017, 2(4): 41-45.
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〔1〕ADAMS HPJR,BENDIVEN B H,KAPPELLE I J,et al. Clissification of sybtype of acute ischemic stroke.Defini. tions fro use in a multi-center clinical TOAST.Trial of Org 10172 in Acute Stroke Ttreatment〔J〕.Stroke,1993,24:35- 41. 〔2〕周衡,李氰晶,王拥军.缺血性脑卒中TOAST亚型分析的 信度检验〔J〕.中华内科杂志,2005,44(11):835-827. 〔3〕中华医学会神经病学分会脑血管病学组,急性缺血性脑 卒中诊治指南撰写组. 中国缺血性脑卒中和短暂性脑缺 血发作二级预防指南(2010)〔J〕. 中华神经科杂志, 2010,43(2):154-160. 〔4〕孟家眉.对脑卒中临床研究工作的建议〔J〕.中华神经精 神科杂志,1988,21(2):57-59. 〔5〕周红英,司俊霞,张红莲.颈动脉超声检查对短暂性脑缺 血发作的诊断价值〔J〕.大理学院学报,2010,9(12):55- 56. 〔6〕国家“九五”攻关课题协作组.急性脑梗死六小时以内的 静脉溶栓治疗〔J〕. 中华神经科杂志,2002,35(4):210- 213. 〔7〕李巷,杨春水,王传明,等.静脉溶栓治疗急性脑梗死的 临床分析〔J〕. 长江大学学报(自然科学版),2014,49 (36):45-46.〔8〕李斗,雷燕妮,单莎林.影响急性脑梗死静脉溶栓治疗预 后的因素〔J〕.中华神经科杂志,2004,37(1):24-26. 〔9〕唐爱群,陈略,朱瑾华,等.尿激酶静脉溶栓治疗急性脑 梗死的疗效观察〔J〕.中国实用神经疾病杂志,2015,18 (16):52-53. 〔10〕陈淑芬,韩翔,史朗峰,等.急性期脑梗死静脉溶栓治疗的 有效性评价〔J〕.中华脑血管病杂志,2009,12(3):4-11. 〔11〕王世芳,肖卫民,吴志强.急性脑梗死静脉溶栓早期治 疗效果的多因素分析〔J〕.中华脑血管病杂志,2012,6 (2):12-15. 〔12〕KIMUR K,LGUCH Y,YAMASHITA S,et al. Atrial fibril? lation asan independent predicter for no enrly recanaliza? tion afterIV- t- PA in acute ischemic stroke〔J〕. Neural sei,2008,267(1-2):57-61. 〔13〕TOMSICK T A,KHATRI P,JOVIN T,et al. Equipoise anong recanalization atrategiec〔J〕. Neurology,2010,74 (13):1069-1076. 〔14〕王素香,王拥军,朱明旺,等.灌注及弥散磁共振成像在 急性缺血性脑卒中的应用〔J〕.中华神经科杂志,2003, 36(3):129-136. 〔15〕常秀红,席妹景,张俊豪,等. 多模式CT指导下的急性 脑梗死尿激酶静脉溶栓研究〔J〕. 中风与神经疾病杂 志,2015,32(4):362-363. 〔16〕高宏章,陈堪愔,何国林,等.尿激酶静脉溶栓治疗急性 脑梗死有效治疗时间窗分析〔J〕.中国实用神经疾病杂 志,2014,17(12):75-77.