Study on Chemical Constituents of Whitfordiodendron filipes

Abstract

Abstract: Objective: The chemical components of Whitfordiodendron filipes were studied in order to search for bioactive ingredients.Methods: The seed of the plant were extracted in the cold-soaked way with ethanol, and the ethanol extraction was partitioned with petroleum ether, acetic ether（EtOAc）and n-butyl alcohol（n-BuOH）. The fraction was separated using silica gel, Sephadex LH-20 column chromatography methods, and their structures were identified based on spectroscopic analyses and chemical properties.Results: Eight compounds of EtOAc and n-BuOH fraction were purified and identified as allantoin（1）, 3-（4-methoxyphenyl） propionic acid（2）, formononetin-7-O-β-D-glucopyranoside（3）,（E）-3, 2′, 4′, 6′ -fourhydroxy-4-methoxy-chalcone-2′-O-Dglucopyranoside（4）, vicioside（5）, D- sucrose（6）, D- 3- O- Quebrachitol（7）, n- tritriacontanol（8）. Conclusion: All these compounds were identified and isolated from the plant for the first time.

Key words: Whitfordiodendron filipes, Chemical constituent, structural identification

CLC Number:

R284

Lu Anmei, Yan Hegui, Hu Jun, Fu Xuemei, Qin Zemin, Guo Jie, Yang Minghui. Study on Chemical Constituents of Whitfordiodendron filipes[J]. , 2017, 2(6): 45-48.

References

〔1〕中国科学院中国植物志编辑委员会. 中国植物志：第40 卷〔M〕.北京：北京科学出版社，1999：130-132. 〔2〕中国科学院植物研究所. 中国主要植物图说：豆科（Whitfordiodendron filipes （Dunn） Dunn in Kew Bull. Misc. Inform）〔M〕. 北京：科学出版社，1955：364. 〔3〕李时珍. 本草纲目：第35卷〔M〕. 北京：人民卫生出版社， 1982：2060. 〔4〕刘玉娇. 猪腰豆、丁座草的化学成分研究及IBX在植物成分转化中的应用〔D〕. 昆明：云南师范大学，2015. 〔5〕张纪宁，杨洁. 黄酮类化合物的生物活性研究进展〔J〕. 伊犁师范学院学报（自然科学版），2009（2）：29-31. 〔6〕张龙，张前军，康文艺，等. 波叶山蚂蝗化学成分研究〔J〕. 中成药，2012，34（10）：1943-1945. 〔7〕闫利华，蒙蒙，张启伟，等.蔓性千斤拔抗氧化活性部位的化学成分研究〔J〕. 中国药学杂志，2013，48（15）： 1249-1254. 〔8〕张亚洲，徐风，梁静，等. 蒙古黄芪中异黄酮类化学成分研究〔J〕. 中国中药杂志，2012，37（21）：3243-3248. 〔9〕潘剑宇，周媛，邹坤，等. 筒鞘蛇菰的化学成分研究〔J〕. 中草药，2008，39（3）：327-331. 〔10〕朱照静，钟炽昌，罗泽渊，等. 苦瓜子有效成分研究〔J〕. 药学学报，1990，25（12）：898-903. 〔11〕陈晓晓，杨尚军，白少岩. 中华猕猴桃根化学成分研究〔J〕. 中草药，2011，42（5）：841-843. 〔12〕邬秋萍，王祝举，付梅红，等. 番泻叶的化学成分研究〔J〕. 中药材，2007，30（10）：1250-1252. 〔13〕姜佩佩，纪明慧，舒火明，等. 猪屎豆的化学成分研究〔C〕/海口：海南省药学会2010年学术年会会议论文集. 2010：59-62.

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