Abstract:

〔Abstract〕Objective: To observe the clinical effect of new supramolecular salicylic acid combined with facial care in the treatment
of acne vulgaris. Methods: A total of 72 patients with acne vulgaris were randomly divided into two groups. The control group
consisted of 34 patients who were treated with new supramolecular salicylic acid for once every two week; there were 38 patients in the
treatment group who were treated with the combination of the new supramolecular salicylic acid and facial care. After a week of the
treatment of salicylic acid, the latter was infused with homemade solution with the help of ultrasonic wave for once or twice a week.
Both of the two groups were treated with salicylic acid for one course. And then a month later, the curative efficacy in the two groups
were compared. Results: The cure rate in the treatment group was significantly higher than that of the control group，and the incidence
of adverse reactions in the treatment group was significantly lower than that in the control group. There were statistically significant
differences between the two groups（P＜0.05）. Conclusion: The combination of new supramolecular salicylic acid and facial care in
the treatment of acne vulgaris is much more effective than the method of using salicylic acid alone, with the ability to improve skin
barrier function and reduce adverse effects. It is worthy of clinical application.

Key words: 〔Key words〕acne vulgaris, new supramolecular salicylic acid, ultrasonic wave, facial care