Chemical Constituents of Aerial Parts of Ternstroemia gymnanthera

Abstract

Abstract: 〔Abstract〕Objective: To study the chemical constituents of aerial parts of Ternstroemia gymnanthera（wight et Arn.）Beddome.
Methods: The chemical constituents of T. gymnanthera were isolated and purified by column chromatography padded with silica gel
and Sephadex LH-20. The structures of the compounds were identified based on the comprehensive analyses of the physicochemical
properties and modern spectral analysis techniques. Results: Five compounds were obtained from ethyl acetate part of 95% ethanol
extract of aerial parts of T. gymnanthera and identified as betulinic acid（1）, 3-epiursolic acid（2）, ursonic acid（3）, α-spinasterol-
β-D-glucopyranoside（4）, and butyl-2-（3, 4-dihydroxyphenyl）acetate（5）. Conclusion: Compounds 2, 3 and 5 were isolated from
the genus Ternstroemia for the first time.

Key words: 〔Key words〕Ternstroemia gymnanthera, aerial parts, chemical constituents, triterpenoids

CLC Number:

R284.1

Liu Ming, Li Huaxuan, Shen Yi, Xiao Chaojiang, Jiang Bei . Chemical Constituents of Aerial Parts of Ternstroemia gymnanthera[J]. Journal of Dali University, 2021, 6(4): 1-3.

References

〔1〕国家中医药管理局《中华本草》编委会. 中华本草：第9
卷〔M〕. 上海：科学技术出版社，1999.
〔2〕李骅轩，崔淑君，肖朝江，等. 厚皮香酚性成分及其镇痛
活性〔J〕. 中成药，2019，41（7）：1582-1586.
〔3〕VENKATESAN T，PARK E J，CHOI Y W，et al. Anti-In⁃
flammatory Activity of Ternstroemia gymnanthera Stem
Bark Extracts in Bacterial Lipopolysaccharide-Stimulated
RAW264.7 Murine Macrophage Cells 〔J〕. Pharm Biol，2017，
55（1）：837-846.
〔4〕IKUTA A，TOMIYASU H，MORITA Y，et al. Ursane- and
Oleanane-Type Triterpenes from Ternstroemia gymnanthera
Callus Tissues〔J〕. J Nat Prod，2003，66（8）：1051-1054.
〔5〕LI H X，XIAO C J，WANG M，et al. Four New Phenyletha⁃
noid Glycosides from Ternstroemia gymnanthera and Their
Analgesic Activities 〔J〕. Phytochem Lett，2019，34：25-29.
〔6〕张树军，时志春，王丹，等 . 紫丁香树叶化学成分研
究〔J〕. 中草药，2018，49（16）：3747-3757.
〔7〕OHNO A，KIZU H，TOMIMORII T. Studies on Nepalese
Crude Drugs. XXI. on the Diterpenoid Constituents of the
AerialPartof Scutellaria discolor COLEBR〔J〕.Chem Pharml
Bull，1996，44（8）：1540-1545.
〔8〕MIN B S，KIM Y H，LEE S M，et al. Cytotoxic Triterpenes
from Crataegus pinnatifida〔J〕. Arch Pharm Res，2000，23
（2）：155-158.
〔9〕熊江，周俊，戴好富，等. 多蕊商陆的化学成分〔J〕. 云南
植物研究，2002，24（3）：401-405.
〔10〕LIEDER B，HANS J，HENTSCHEL F，et al. Biological
Evaluation of Natural and Synthesized Homovanillic Acid
Esters as Inhibitors of Intestinal Fatty Acid Uptake in Dif⁃
ferentiated Caco-2 Cells〔J〕. Molecules，2019，24（19）：
3599.
〔11〕刘蒲，王国权. 五环三萜类化合物的药理作用研究进
展〔J〕. 海峡药学，2018，30（10）：1-6.
〔12〕周亚敏，林丽美，夏伯候. 白桦脂酸制备方法和药理活
性研究进展〔J〕. 天然产物研究与开发，2016，28（6）：
978-985.
〔13〕RAMALHO S D，DE SOUSA L R，NEBO L，et al. Triter⁃
penoids as Novel Natural Inhibitors of Human Cathepsin
L〔J〕. Chem Biodivers，2014，11（9）：1354-1363.

[1]	Wang Tian, Ye Zuyue, Yang Huiyun, Wang Le, Wang Fushen. Chemical Constituents of Flavonoids from Medicinal Plant Gentiana yunnanensis [J]. Journal of Dali University, 2021, 6(4): 4-6.
[2]	Zhu Qijie, Lang Lijuan, Jiang Bei, Shen Yi, Wang Ying, Xiao Chaojiang. Chemical Constituents of the Fruits of Wild Crataegus scabrifolia [J]. Journal of Dali University, 2021, 6(4): 7-9.
[3]	Ning Xiao，Wang Min,Cui Shujun,Xiao Chaojiang,Jiang Bei . Chemical Constituents of Underground Parts of Cimicifuga yunnanensis [J]. Journal of Dali University, 2020, 5(2): 23-26.
[4]	Zhao Yueli, Dong Hongqiang, Zhang Lansheng . Chemical Constituents from the Ethyl Acetate Portion of Rumex japonicus [J]. Journal of Dali University, 2020, 5(2): 27-30.
[5]	Liu-Jian, XIAO Chao-Jiang, ZHANG Fen-Fen, CUI Chu-Jun, LI Yang, JIANG Bei. A Study on Chemical Constituents of Hypericum uralum [J]. , 2018, 3(4): 1-4.
[6]	Zhang Panpan, Xiao Chaojiang, Liu Jian, Qiu Lin, Shen Yi, Dong Xiang, Jiang Bei*. Studies on Antimalarial Constituents of Dendrobenthamia capitata [J]. Journal of Dali University, 2018, 3(2): 1-5.
[7]	Chen Hao, Liu Xiaowei, Shen Yi, Cui Shujun, Xiao Chaojiang. Study on β-Hematin Formation Inhibition Activity of Radix Campylotropidis Hirtellae [J]. , 2018, 3(2): 6-9.
[8]	Chen Yafeng, Zhang Zuzhen, Wang Fusheng. Study on Chemical Components from n-butanol Fraction of Medicinal Plants Triplostegia glandulifera [J]. , 2017, 2(4): 9-11.
[9]	Fu Chen, Li Fengfeng, Wang Fusheng. Study on Chemical Constituents of Campylotropis trigonoclada [J]. J4, 2016, 1(4): 8-13.
[10]	Chu Qiao , Xia Conglong. Chemical Constituent of Swertia angustifolia Buch.II [J]. J4, 2016, 1(4): 14-16.
[11]	Chen Liyuan, Li Shuixian, Xia Conglong. Chemical Constituents of Swertia angustifolia Buch. [J]. J4, 2015, 14(2): 1-3.
[12]	CHEN Jian-Yong, LIU Guang-Ming, ZHANG Yu, HAO Xiao-Jiang, HE Hong-Ping. Chemical Constituents of Stellera chamaejasme [J]. J4, 2014, 13(8): 1-3.
[13]	SHI Gui-Rong, GUO Mei-Xian, LI Dong-Mei, LIU Xi, YANG Jing, LIU Guang-Ming. Chemical Constituents from Pinecone of Pinus kesiya R. [J]. J4, 2014, 13(2): 1-2.
[14]	CHENG Xia, XIAO Chao-Jiang, SUN Jun-Zhe, JIANG Bei. Study on the Chemical Constituents of Astragalus balfourianus [J]. J4, 2014, 13(2): 3-5.
[15]	WU La-Bin, HUANG Bo, XIAO Chao-Jiang, DONG Xiang, JIANG Bei. Chemical Constituents of the Root of Foeniculum vulgare [J]. J4, 2013, 12(9): 1-3.