Journal of Dali University ›› 2022, Vol. 7 ›› Issue (8): 79-82.

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Analysis of Distribution and Antibiotic Resistance of Mycoplasma pneumoniae Infection in a Hospital in Dali City from 2015 to 2020

Jia Han1 Xu Jiaqi1 Li Fuxing1 Hu Shenghe2*   

  1. 1. Clinical College Dali University Dali Yunnan 671000 China 2. Department of Laboratory Medicine The First Affiliated Hospital of Dali University Dali Yunnan 671000 China

  • Received:2021-10-20 Revised:2022-03-14 Online:2022-08-15 Published:2022-09-16

Abstract: Objective: To analyze the clinical distribution characteristics and antibiotic resistance changes of Mycoplasma pneumoniae infection in the First Affiliated Hospital of Dali University from 2015 to 2020, and to provide reference for clinical medication. Methods:Expectorated or aspirated sputum samples in the First Affiliated Hospital of Dali University from 2015 to 2020 were isolated and cultured, strains in them were detected, and antibiotics susceptibility was applied for all isolated bacteria. And then the data were statistically analyzed. Results: A total of 185 strains of Mycoplasma pneumoniae were isolated, and the annual distribution showed a downward trend year by year. Patients mainly came from the Department of Respiratory Medicine and the Department of Infectious Diseases. The age mainly ranged from 41 to 80. The antibiotics susceptibility results showed that there was a statistically significant difference in the overall resistance rates of Mycoplasma pneumoniae to minocycline, acetylspiramycin, ciprofloxacin and clindamycin in this hospital from 2015 to 2020(P<0.05). Conclusion: The resistance trend of Mycoplasma pneumoniae to antibiotics is stable from 2015 to 2020, and the dynamic monitoring of resistance should be strengthened to guide the rational use of antibiotics in clinical practice.

Key words: Mycoplasma pneumoniae, infection distribution, drug resistance

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