J4 ›› 2011, Vol. 10 ›› Issue (12): 10-11.

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Chemical Constituents of the Polar Part of Swertia Punicea Hemsl

Objective: To investigate the chemical constituents of Swertia punicea Hemsl. Methods: The compounds were isolated and purified by silica gel, ODS, MCI and Sephadex LH-20 column chromatography, and their structures were elucidated by TLC, UV,1H-NMR, and 13C-NMR analysis. Results: Six compounds were isolated and identified from butanol fraction of Swertia punicea extract, and they are 1,5,8-trihydroxy-3-methoxyxanthone (I), 1,3,8-trihydroxy-5-methoxyxanthone (II), 1,8-dihydroxy-3,5-dimethoxyxanthone(III), 1,3,5,8 tetrahydroxyxanthone(IV), oleanolicacid(V)and sweroside(VI). Conclusion: Compound(II) was obtained from this plant for the first time.   

  1. School of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China
  • Received:2011-08-23 Revised:2011-09-05 Online:2011-12-15 Published:2011-12-15

Abstract:

Objective: To investigate the chemical constituents of Swertia punicea Hemsl. Methods: The compounds were isolated and purified by silica gel, ODS, MCI and Sephadex LH-20 column chromatography, and their structures were elucidated by TLC, UV,1H-NMR, and 13C-NMR analysis. Results: Six compounds were isolated and identified from butanol fraction of Swertia punicea extract, and they are 1,5,8-trihydroxy-3-methoxyxanthone (I), 1,3,8-trihydroxy-5-methoxyxanthone (II), 1,8-dihydroxy-3,5-dimethoxyxanthone(III), 1,3,5,8 tetrahydroxyxanthone(IV), oleanolicacid(V)and sweroside(VI). Conclusion: Compound(II) was obtained from this plant for the first time.

Key words: Swertia punicea Hemsl, chemical constituents, xanthone

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