Abstract:

Objective: To explore the chemical constituents of tuber of Isodon adenantha. Methods: Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral analysis and chemical evidences. Results: Five compounds were obtained from ethyl acetate fraction of the extract from tuber of I. adenantha and identified as 8 （17）, 13-ent-labdadien-15→16-lactone-19-oic acid (1), ursolic acid （2） ,β-sitosterol （3）, ferulic acid （4）and coniferyl aldehyde （5）. Conclusion: Compounds 1 -5 are isolated from the underground part of I. adenantha for the first time, and the compounds 1, 4, and 5 were firstly obtained from this plant.

Key words: Isodon adenantha, terpenoids, phenols