Clinical Study on Non-alcoholic Fatty Liver Disease and Acute Coronary Syndrome

Abstract

Abstract:

Objective: To study the correlation of non-alcoholic fatty liver disease（NAFLD）and acute coronary syndrome（ACS）
pathogenesis. Methods: One hundred and forty cases of ACS with NAFLD hospitalized in our hospital from January 2006 to December
2013 were divided into NAFLD group（n=80）and non NAFLD group（n=60）, the results were compared by vascular ultrasound
detection rate of carotid plaque. ACS was divided into three clinical subgroups of unstable angina pectoris（UA）, acute ST segment
elevation myocardial infarction（STEMI）, non ST segment elevation acute myocardial infarction（NSTEMI）. And the incidence of
NAFLD was observed in each subgroup. Riglyceride（TG）, cholesterol（TC）, low density lipoprotein（LDL- C） levers have no
difference in both NAFLD group and non NAFLD group. Results: The detection rate of carotid plaque in ACS combined with NAFLD
group was significantly higher than that in non NAFLD group（85% vs 40%）, there was significant difference between two groups（P<
0.01）; there was no statistically significant in the three subgroups of ACS the incidence of NAFLD and non NAFLD incidence rate
difference（P > 0.05）; group NAFLD, TG, TC, LDL-C level was significantly higher than that of non NAFLD group（P < 0.05）.
Conclusion: NAFLD patients have high risk carotid atherosclerosis and hyperlipidemia appears, which is a potential risk factor for
coronary heart disease ACS, timely intervention of NAFLD patients can be benefit in the prevention and treatment of cardiovascular
diseases.

Key words: non-alcoholic fatty liver disease, acute coronary syndrome coronary heart disease, carotid artery plaque

CLC Number:

R541.4

Xiong Liping, Liu Zhengxing. Clinical Study on Non-alcoholic Fatty Liver Disease and Acute Coronary Syndrome[J]. J4, 2015, 14(8): 18-21.

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