Abstract: Molecular deposition filming flooding(MDFF) is a novel oil recovery technique. To investigate the differences between molecular deposition filming flooding agent and mono-quaternaries in interfacial interactions, microelectrophoresis method was applied in studying the electrostatic behavior of kaolinite/water
and aspaltene p-xylene solution/water interfacial action. Results show that the Zeta potential can reflect differences between molecular deposition filming flooding agent and mono-quaternaries in interfacial electrostatic interaction and Vander Waals force interaction. The interaction of quaternaries and asphaltene pxylene solution/water interface is larger than that of quaternaries and kaolinite/water interface. The Vander Waals force plays
more important role in interaction of quaternaries and asphaltene p-xylene solution/water interface than that of quaternaries and Kaolinte/water interface. The interfacial interaction has such a sequence as follows: MDFF agent>tetramethylammonium bromide > tetraethylammonium bromide > tetrabutylammonium bromide. MDFF agent differs from mono-quaternaries mainly because of its larger charge amount, while mono-quaternaries
differ from each other because of the Vander Waals force between each species and interfaces.

Key words: molecular deposition filming flooding agent, mono-quaternaries, interfacial interaction, Zeta potential