Journal of Dali University ›› 2023, Vol. 8 ›› Issue (8): 11-14.

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Study on Chemical Constituents of Leptodermis pilosa

Shi Kaixuan1,2, Li Jing1,2, Ling Haowei1,2, Liu Rong1,2, Xiao Chaojiang1,2, Jiang Bei1,2*   

  1. (1. Yunnan Key Laboratory of Screening and Research on Anti-Pathogenic Plant Resources from Western Yunnan, Dali, Yunnan 671000, China; 2.College of Pharmacy, Dali University, Dali, Yunnan 671000, China)

  • Received:2023-01-09 Revised:2023-02-26 Online:2023-08-15 Published:2023-07-11

Abstract: Objective: To study the chemical constituents of the whole-plant of Leptodermis pilosa. Methods: Silica gel, MCI, and Sephadex LH-20 column chromatography were used to isolate and purify the chemical constituents of L. pilosa. The structures were identified based on physicochemical properties and modern spectroscopic analysis techniques. Results: Eight compounds were isolated from the ethyl acetate fraction of the 75% ethanol extract of the whole-plant of L. pilosa and identified as oleanolic acid(1), 2?琢 -hydroxyloleanolic acid(2), arjungenin(3), scopoletin(4), methyl caffeate(5), syringic acid(6), salicylic acid(7), and daucosterol(8). Conclusion: All the compounds were isolated from L. pilosa for the first time, and compounds 2-7 were first isolated from genus Leptodermis.

Key words: "> , Leptodermis pilosa">;"> chemical constituents">;"> phenols">;"> triterpenoids

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