关键词: font-family:宋体, ">定量font-family:", ">CTfont-family:宋体, ">, 慢性肾脏病, 骨密度, 受试者操作特征曲线分析

Abstract: Objective： To investigate the value of quantitative CT in measuring bone mineral density in patients with chronic kidney disease（CKD）. Methods： From January 2019 to December 2021， CKD patients（case group） diagnosed in Chongqing Changshou District People's Hospital and healthy volunteers（control group） who underwent bone mineral density examination at the same time were selected as the research objects. The bone mineral density was measured by dual-energy X-ray absorptimetry and quantitative CT. The research objects were divided into normal bone mass subgroup， low bone mass subgroup and osteoporosis subgroup according to the T value. According to the stage of CKD patients， the case group were divided into CKD stage 1-2 subgroup， CKD stage 3 subgroup， CKD stage 4 subgroup and CKD stage 5 subgroup. The bone mineral density of each group was compared， and the diagnostic value of quantitative CT for osteoporosis in CKD patients was evaluated by the receiver operator characteristic curve（ROC curve）. Results： The overall differences of bone mineral density in different bone mass subgroups were statistically significant， and the differences between groups were also statistically significant（P<0.05）. There was a statistically significant difference in the overall bone mineral density between the control group and different CKD subgroups， and there was a statistically significant difference in the bone mineral density between CKD stage 4 subgroup， CKD stage 5 subgroup and the control group （P<0.05）. The ROC curve results showed that the sensitivity and specificity of quantitative CT in detectingbone mineral density for osteoporosis in CKD patients were 80.99% and 83.10%， respectively， with good diagnostic efficacy. Conclusion： Quantitative CT can be used to measure bone mineral density in CKD patients， which has high diagnostic value for osteoporosis in CKD patients.

Key words: font-family:Times New Roman, ">quantitative CTfont-family:Times New Roman, ">, font-family:Times New Roman, "> chronic kidney diseasefont-family:Times New Roman, ">, font-family:Times New Roman, "> bone mineral densityfont-family:Times New Roman, ">, font-family:Times New Roman, "> analysis of receiver operator characteristic curve