Abstract:

Objective：To investigate the clinical results of cervical LEEP（loop electrosurgical excisional procedure）and microwave therapy in treatment of class III cervical erosion. Methods：One hundred and twenty patients with class III cervical erosion were randomly divided into treatment group（LEEP therapy）and control group（traditional microwave therapy），with 60 cases in each group. Blood loss，effects on exuvial hemorrhage at 15 days and 60 days postoperative，as well as the rate of high-risk HPV infection at 90days postoperative were evaluated. Results：There were 20 cases of HPV infection in LEEP group，2 cases of exuvial hemorrhage were observed at 15 d postoperative，all cases of cervical wounds were 100% healed at 60 d and 90 d postoperative （healing rate 100%）；2 cases （10%）showed high-risk HPV persistent infection at 90 d postoperative. There were 18 cases of HPV infection in
control group，12 cases of exuvial hemorrhage were observed at 15 d postoperative，42 cases of cervical wounds were 100% healed at 60 d and 90 d postoperative （healing rate 70%），meanwhile in 18 cases，about 1/3 to 1/2 of wound healed，and 4 patients did not heal at all；6 cases （30%）showed high-risk HPV persistent infection at 90 d postoperative. The data showed that there were statistic significance between the two groups in healing effect and infection rate （P<0.05）. Conclusion：Compared to the microwave therapy，LEEP therapy got better curative effect with shorter healing time and lower HPV persistent infection rates in treatment of class III cervical erosion.

Key words: loop electrosurgical excision procedure（LEEP）, class III cervical erosion, microwave treatment