Abstract:

Objective: To investigate the prevalence and drug resistance of pathogens infection in surgical intensive care unit
（SICU）ward in the Hospital of Chuxiong Prefecture from 2009 to 2012, and to provide help for rational clinical use of antibacterial drugs. Methods: Pathogenic bacteria cultured in SICU from 2009 to 2012 were identified and conducted the drug sensitive test by applied automatic bacteria identification system （biomerieux France）; data were statistically analyzed by WHONET 5.6 software. Results: There were 893 strains of pathogens detected in the 4 years, with 141 strains of gram-positive bacteria （15.7%）and 752 strains of gram-negative bacteria. Pathogens were isolated from samples of sputum, urine, blood and bile, while sputum sample made up the majority. The isolated rate of multi-resistant bacterium was 22.1% （2009）, 30.9% （2010）, 47.5% （2011）, 54.3%（2012）, respectively. Under the drug sensitive test, the rate of pathogen resistance to normal antibacterial drugs was high, but the
enterobacteriaceae and vancomycin resistant enterococci resistant to carbon penicillium effect of enzyme antibiotics were not found. Conclusion: The pathogen in SICU was mainly gram-negative bacteria, and with high proportion of multi-resistant bacterium, isolated rate of multi-resistant bacterium raised year by year, we should strengthen the regional surveillance of bacterial resistance to guide clinical medication.

Key words: surgical intensive care unit（SICU）ward, pathogen, bacteria distribution, drug resistance