Clinical Observation of rhEGF Treating Serious Contusion Wound

Abstract

Abstract:

Objective: To observe the effect of recombinant human epidermal growth（rhEGF） factor on serious contusion wounds
and its adverse reactions. Methods: Fifty-six cases with one hundred and forty-eight wounds were divided into two groups. On the
base of routine treatment, rhEGF was added to treatment group and 0.05% iodophor disinfection solution was conducted to control
group. The healing time of the two groups was observed respectively. Results: The average healing time for shallow Ⅱ degree
contusion wounds was 9.56±1.74 days for treatment group and 12.75±3.18 days for the control. The average healing time for deep II degree contusion wounds was 18.16±2.67 days in treatment group compared with 21.26±3.83 days in the control. The healing time was significantly shorter（P < 0.05, 0.01）in rhEGF group than the control. The effective rate in rhEGF group was 90.72%. Conclusion:rhEGF can promote healing in Ⅱ degree contusion wounds, especially for deep Ⅱ degree wounds.

Key words: rhEGF, wound healing, wound

CLC Number:

R641

Zhang Chen, Chai Shaoqiang, Ma Binbin. Clinical Observation of rhEGF Treating Serious Contusion Wound[J]. J4, 2015, 14(4): 47-49.

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