Abstract:

Objective: To compare and evaluate the significance of monitoring maintained hemodialysis（MHD）patient's serum intact
parathyroid hormone through the detection of MHD patient's serum intact parathyroid hormone（iPTH）and the concentration of biological activity intact parathyroid hormone l-84（PTH 1-84）. Methods: 32 MHD patients from Affiliated Hospital of Dali University were enrolled in this study, the control group included 30 healthy people. The concentrations of serum iPTH and PTH（1-84）were detected by Cobas e2010 automatic chemiluminescence analyzer. And all data was analyzed by SPSS13.0 software for statistical analysis. Results: The serum levels of iPTH and PTH（1-84）were higher in the maintained hemodialysis group than in the control group, difference was statistically significant（P<0.01）, the iPTH of the dialysis group was higher than that of PTH（1-84）, and the difference was statistically significant（P<0.05）, in MHD patients，the serum iPTH and PTH（1-84）showed a significant correlation respectively（r=0.927 7，P<0.01）, there was no significant difference between normal control group iPTH and PTH（1-84）（P>0.05）.Conclusion: In MHD patients, the concentrations of serum iPTH and 1-84（PTH）were significantly higher and there was a positive correlation between them, so the value of PTH（1-84）diagnosis of renal osteodystrophy is better than iPTH.

Key words: maintenance hemodialysis, intact parathyroid hormone（iPTH）, biological activity intact parathyroid hormone l-84