Therapeutic Effects of Ganlong Capsule on Liver Fibrosis in Rats Induced by Pig Serum

Abstract

Abstract:

〔Abstract〕Objective: To investigate the therapeutic effect of Ganlong capsule on rat liver fibrosis induced by pig serum. Methods:
After the rat liver fibrosis model was induced by porcine serum, rats with liver fibrosis were treated with different concentrations of
Ganlong capsule. The liver, spleen, thymus were weighed and their index were calculated. The index of liver function was detected with
the kit, including γ-glutamyl transpeptidase and malondialdehyde. Enzyme-linked immunosorbent assay（ELISA）was used to detect
the indexes of liver fibrosis including Laminin, Hyaluronic acid, PCⅢ, Ⅳ-C, Type collagen and transforming growth factorβ1. Results:
Ganlong capsule had reduced the content of LN, PCⅢ and Ⅳ-C in fibrosis serum of rats, decreased the content of γ-GT and HA, and
increased the content of COL-Ⅰ in liver tissue. Conclusion: Ganlong capsule has certain therapeutic effects on liver fibrosis in rats.

Key words: 〔Key words〕Ganlong capsule, liver fibrosis, index of liver function, index of liver fibrosis

CLC Number:

R965

Li Yan, Shao Mingyuan, Guo Chao, Yang Qiangli, Cao Chang'e, Lai Yong. Therapeutic Effects of Ganlong Capsule on Liver Fibrosis in Rats Induced by Pig Serum[J]. , 2018, 3(10): 13-17.

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