Study on the Correlation between Red Blood Cell Count and Hypertension at High Altitude

doi:10. 3969 / j. issn. 2096-2266. 2021. 08. 012

Abstract

Abstract: Objective: To study the correlation between red blood cell count and blood pressure and hypertension at high altitude.
Methods: All employees and retired workers in a factory in Dali were invited to participate in this study, and a standardized
questionnaire was used to collect the participants’ demographic information, disease history, smoking and drinking habits, family
history of hypertension and so on. SPSS 19.0 was used for multiple linear regression analysis and Logistic regression analysis.
Results: The 1 395 participants included 546 women (39.1%) and 460 hypertensive patients (33.0%). Multiple linear regression
analysis showed that after adjusting for covariates, red blood cell count was positively correlated with systolic and diastolic blood
pressure, and hemoglobin level was positively correlated with diastolic blood pressure. Logistic regression analysis found that after
adjusting for covariates, red blood cell count was independently associated with the increased risk of hypertension. For each 1×1012/L
increase in red blood cell count, the risk of hypertension increased by 92% (OR=1.920, 95%CI 1.161-3.175, P=0.011), while
hemoglobin was not associated with the risk of hypertension (P= 0.361). Conclusion: Red blood cell count was positively correlated
with blood pressure and risk of hypertension at high altitude. Long-term chronic hypoxia at high altitude may be involved in the
regulation of blood pressure and the pathogenesis of hypertension by stimulating erythrocytosis.

Key words: blood pressure, hypertension, red blood cell count, hemoglobin, high altitude

CLC Number:

R749

Hu Naiqing, Lü Jinlin, Yin Xueyan, Li Lihua. Study on the Correlation between Red Blood Cell Count and Hypertension at High Altitude[J]. Journal of Dali University, 2021, 6(8): 54-57.

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