Table of Content

15 August 2020, Volume 5 Issue 8

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Preliminary Analysis of Epidemic Situation of COVID-19 in Yunnan Province

Li Fuxing, Xie Kexin, Zhang Yulin, Zhao Weidong

2020, 5(8):  1-6.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 001

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〔Abstract〕Objective: To analyze the epidemiological characteristics and trends of the novel coronavirus pneumonia（COVID-19）in
Yunnan province. Methods: From January 24, 2020 to April 14, 2020, the epidemiological data of COVID-19 were collected from the
website of Health Commission of Yunnan Province. Results: As of April 14, 2020, the total number of confirmed cases, current
confirmed cases and newly confirmed cases in Yunnan province first increased and then decreased. At first, the cause of disease
changed from imported infection to secondary infection. With global spread of the COVID-19, the cause of disease has changed from
secondary infection to imported infection of overseas. In Yunnan, the cure rate is 95.6% which is higher than the national level, and the
mortality rate is 1.1% which is lower than the national level. Conclusion: The overall trend for frequency of COVID-19 shows a
decreasing pattern. However, the epidemic situation is not completely over yet. The oversea epidemic situation is critical with the
increase of non-symptom patients. With workers returning back to work and students returning back to school, we will face with
tremendous COVID-19 pressure and challenges. We still need to pay attention to personal protection, be alert to the input of overseas
cases, and do a good job in monitoring the asymptomatic infected people to prevent the epidemic from rebounding.


Epidemiological Characteristics of COVID-19 in Jilin Province

Ma Yingying,Li Lijuan

2020, 5(8):  7-11.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 002

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〔Abstract〕Objective: To explore the epidemiological characteristics of the novel coronavirus pneumonia（COVID-19）in Jilin
province, and to provide a basis for the prevention and control measures during the recovery period of the epidemic. Methods: Using
descriptive epidemiological methods, Excel and SPSS 23.0 were used to organize and statistically analyze the information of all novel
coronavirus pneumonia cases as of May 16, 2020 in Jilin province, and OriginPro 8.0 was used to draw statistical graph. Results: The
gender ratio of local cases was 1.1 : 1, and the largest number of cases was over 40 years old and under 60 years old（55 cases, 47.0%）,
mainly in Changchun city（45 cases, 36.3%）, Jilin city（36 cases, 29.1%）, and Siping city（15 cases, 12.1%）. Family-aggregated
cases accounted for 48.4% of the total number of cases. The ratio between non-imported cases and imported cases was 2.2 : 1, and from
February 2, 2020, the case type had changed from imported to non-imported. Among imported cases, Russia（11 cases, 57.9%）was
the main source country, and Jilin city（11 cases, 57.9%）was the region with the most cases. Conclusion: The number of novel
coronavirus pneumonia cases in Jilin province is the same for males and females, mainly young and middle-aged, and the disease has
been detected in all areas except Baishan city and Changbai Mountain Administrative Committee. The cases are mostly non-imported
and have the characteristics of family aggregation. The time of imported cases coincided with the time of the lockdown of Wuhan, and
the second outbreak occurred in the local area. The prevention and control of the situation is still a challenge. The focus should be the
possible outbreaks after resuming offline education, imported cases and outbreaks in local areas.


Nursing Care of COVID-19 Patients During Medical Observation

Zeng Qi, Sun Yaping, Lu Nihong

2020, 5(8):  12-15.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 003

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〔Abstract〕Objective: To study the nursing experience of the novel coronavirus pneumonia（COVID-19）patients during medical
observation. Methods: 250 novel coronavirus pneumonia patients were observed by medical observation center in the sixth affiliated
hospital of Dali university from January 30 to March 20, 2020, including their medical service, isolation protection, psychological care
and life support. Results: The careful and thoughtful nursing and care of the medical staff met the needs of the patients in an all-round
way, solved all the difficulties for them, and got the affirmation of our work from the patients. Conclusion: The humanistic care has
really made the patients feel being cared and loved.


Study on the Optimum Extraction Technology of Salvia yunnanensis Based on the Function of Promoting Blood Circulation

Zhang Yanru,Bai Xue,Cao Bo,Lin Yawen,Zhang Haizhu

2020, 5(8):  16-20.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 004

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〔Abstract〕Objective: To study the optimum extraction technology for promoting blood circulation of Salvia yunnanensis. Methods:
L 9 （3 4 ）orthogonal experiment and rat platelet aggregation experiment in vitro were used to investigate the effects of four factors, i.e.
material-liquid ratio, extraction time, extraction times and methanol concentration on the components of Salvia yunnanensis promoting
blood circulation and removing blood stasis, and the platelet aggregation effect was also detected. GraphPad Prism 6.01 software was
used to fit the optimum half effective concentration（EC 50 ）and select the optimum extraction process. Results: The optimum extraction
conditions were as follows: the ratio of material to liquid was 1 : 15, the concentration of methanol was 100%, the extraction time was 30
minutes, the extraction times were 2 times, and the EC 50 of ADP induction was 4.141 mg/mL. Conclusion: The optimum extraction
process for promoting blood circulation of Salvia yunnanensis was preliminarily determined, which provided experimental basis for the
full development and application of its resources.


UPLC-MS/MS Fingerprint Study of Miao Medicine Periploca forrestii

Liu Yao, Hu Die, Cheng Chun, Liu Jie, Xu Jian

2020, 5(8):  21-26.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 005

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〔Abstract〕Objective: To establish a UPLC-MS/MS fingerprint analysis method for Periploca forrestii and provide scientific basis for
its quality control and evaluation. Methods: An ACQUITY UPLC CSH C 18 column（150 mm×3.0 mm, 1.7 μm）was used for gradient
elution, using water（A, 0.2% formic acid）-acetonitrile（B）as mobile phase; column temperature was 25 ℃, and injection volume was
2 μL. The similarity evaluation was carried out by using "The Similarity Evaluation System for Chromatographic Fingerprint of
Traditional Chinese Medicine（Version 2004A）". Results: The common pattern of fingerprint of Periploca forrestii was established,
among which 19 common peaks were confirmed, and 2 common peaks were identified. The similarities were investigated and their
similarities were above 0.900. Conclusion: The UPLC-MS/MS fingerprint analysis method of Periploca forrestii was established for the
first time. This study has a certain reference value for controlling and evaluating the quality of Periploca forrestii.


Efficacy Analysis of Fluconazole and Voriconazole in Treating Oral Candida Infection Complicated with AIDS

Chen Yonggang,Lu Hongwei,Luo Ji,Liu Xing

2020, 5(8):  27-30.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 006

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〔Abstract〕Objective: To investigate the therapeutic effect of fluconazole and voriconazole on oral candida infection in AIDS patients,
and to provide reference for clinical rational drug use. Methods: Retrospective analysis was conducted on the treatment data of AIDS
patients complicated with oral candida infection in the sixth affiliated hospital of Dali university in 2018. Data were collected and
analyzed by SPSS 21.0, including clinical efficacy, adverse reactions and cost-effectiveness analysis. Results: There was no
statistically significant difference in treatment effects between the two groups（P>0.05）, no statistically significant difference in adverse
reactions（P>0.05）, but statistically significant difference in pharmacoeconomics（P<0.05）. Conclusion: When fluconazole and
voriconazole were used to treat AIDS-associated oral candidiasis infections, there was no statistically significant difference in efficacy
and adverse reactions, but the cost-effectiveness of fluconazole was lower and the sensitivity analysis results were unchanged, so it has
more pharmacoeconomic advantages.


Effects of Periplaneta americana Extract on Pulmonary Fibrosis Induced by Bleomycin in Rats

Yang Yongshou,He Zhengchun,Xiao Peiyun

2020, 5(8):  31-37.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 007

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〔Abstract〕Objective: To investigate the effects of anti-pulmonary fibrosis active extract（ML-HB）of Periplaneta americana on
bleomycin-induced pulmonary fibrosis in rats. Methods: Male SD rats were randomly divided into the normal group, the model group
and the ML-HB group（60 mg/kg, qd）. The pulmonary fibrosis model was established through tracheotomy with bleomycin. The rats
were intervened by treating with intraperitoneal administration after 24 h of modeling. On the 30 th , 45 th , 60 th and 75 th day after
administration, 10 rats were randomly sacrificed in each group. Their lung index was determined, tumor necrosis factor-α（TNF-α）
and transforming growth factor-β1（TGF-β1）in lung homogenate were detected by ELISA, and α-smooth muscle actin（α-SMA）
and type I collagen（ColⅠ）were observed by immunohistochemical staining. Results: Compared with the model group, the ML-HB
group showed lower expressions of lung index, TNF-α, TGF-β1, α-SMA and ColⅠ, and the difference were statistically significant（P
＜0.05）. Conclusion: ML-HB can reduce the expression of TNF-α, TGF-β1, α-SMA and ColⅠ, and delay pulmonary fibrosis
development.


Observation and Analysis of the Effects of Periplaneta americana Extract on Human Demodex

ChengYun,Wei Zhixin,Zhang Qian,Zou Yufeng,Yang Qian,Shao Weizai,Yang Yimei

2020, 5(8):  38-42.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 008

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〔Abstract〕Objective: To evaluate whether Periplaneta americana extract can kill Demodex, and to explore the best concentration
with the minimal side effects. Methods: The Demodex were collected with adhesive cellophane tape, and changes in the number of
Demodex deaths before and after acaricide shooting were microscopically observed. Results: The extract of Periplaneta americana has
a good effect on killing Demodex. The optimum concentration is 2%. Conclusion: The extract of Periplaneta americana can be used to
kill Demodex on the face. The experiment method of acaricide shooting is simple, practical and effective.


Exploration on the Reform of Human Parasitology Teaching Mode under the Background of Medical Education Cooperation

Li Qian, Zhang Li, Li Hailong, Lü Yan, Yang Yimei

2020, 5(8):  43-47.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 009

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〔Abstract〕Objective: Under the background of deepening the cooperation of medical education and further promoting the reform and
development of medical education, the course of human parasitology changes the traditional medical education model, establishes a
medical talent training model that adapts to the characteristics of the industry, in order to cultivate solid theoretical and practical
medical personnel. Methods: The human parasitology course comprehensively reformed the teaching model from the aspects of
teaching content, teaching methods, examination methods, Internet + application, etc., and the learning performance of two grades were
compared to analyze the teaching effect. Results: The academic performance of the 2015 medical student was better than that of the
2014 medical student. The difference was statistically significant（P＜0.05）, and there were good feedbacks in the supervision
evaluation and student satisfaction survey. Conclusion: The comprehensive reform teaching mode of human parasitology curriculum is
combined with clinical practice, and the teaching reform effect is good.


CYP2C19 Gene Polymorphism in Patients with Cerebral Infarction in Chuxiong Area of Yunnan Province

Li Wenwu, Lü Xiujuan

2020, 5(8):  48-51.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 010

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〔Abstract〕Objective: To investigate the polymorphism of CYP2C19 gene in patients with acute cerebral infarction in Chuxiong area
of Yunnan province. Methods: The CYP2C19*1, c.681 G A and *1, c.636 G A; CYP2C19*2, c.681 G A; CYP2C19*3, c.636 G
A gene polymorphism was detected with PCR in 251 patients with acute cerebral infarction. Results: There were 114 cases 45.42%
of fast metabolic type with CYP2C19*1/*1 gene. There were 95 cases 37.85% , 13 cases 5.18% , 4 cases 1.59% of intermediate
metabolic type with CYP2C19*1/*2, *1/*3, *2/*2 genes and 23 cases 9.16% and 2 cases 0.80% of slowly metabolic type with
CYP2C19*2/*3 and*3/*3 genes. Conclusion: The mainly polymorphisms of CYP2C19 gene in patients with acute cerebral infarction
in Chuxiong area of Yunnan province are fast metabolic*1/*1 GG/GG , intermediate*1/*2 GG/GA , slow metabolic *2/*3 GA/GA .

Application of Preperitoneal Water Injection in Laparoscopic Surgery for Children's Inguinal Hernia

Jin Jiebo, He Tao

2020, 5(8):  52-53.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 011

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〔Abstract〕Objective: To investigate the value of preperitoneal water injection in laparoscopic surgery for children's inguinal hernia.
Methods: From January 2018 to December 2018, 40 patients with inguinal hernia were treated with this method. Results: All patients
underwent successful operations. There were no complications such as recurrence after 6-12 months of follow-up. Conclusion:
Laparoscopic surgery for children's inguinal hernia after peritoneal water injection is simple and easy to do, and has a certain
significance for protecting the vas deferens.


Application Study of Anesthesia Depth Monitoring in Hip Fracture Surgery of Elderly Patients

Sun Hao, Li Yan, Bo Huilong, Gu Qin

2020, 5(8):  54-57.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 012

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〔Abstract〕Objective: To explore the clinical application effect of anesthesia depth monitoring in hip fracture surgery of elderly
patients. Methods: From August 2018 to September 2019, 60 elderly patients who underwent proximal femoral nail antirotation
（PFNA）internal fixation in Suzhou xiangcheng people's hospital were selected as the research subjects. According to the random
number table method, 60 elderly patients were divided into a control group（conventional anesthesia monitoring）and an experimental
group （anesthesia depth monitoring）. The bispectral index（BIS） score, intraoperative awareness rate, anesthetic dosage and
postoperative recovery time were compared. Results: The BIS score of the experimental group was higher than that of the control group,
and the difference was statistically significant（P＜0.05）. The intraoperative awareness rate, the total dosage of anesthetics and the
postoperative recovery time of the experimental group were significantly lower than that of the control group, and the differences were
statistically significant （P＜0.05）. Conclusion: The application of anesthesia depth monitoring in elderly patients with PFNA internal
fixation is satisfactory, and it is worthy of further clinical application.


Application of Pelvic Floor Ultrasound in Evaluating Effect in Early Postpartum Rehabilitation Therapy

Dai Qingli

2020, 5(8):  58-61.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 013

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〔Abstract〕Objective: To explore the application of perineal real-time three-dimensional pelvic floor ultrasound measurement of
levator ani hiatus in the evaluation of early postpartum rehabilitation therapy. Methods: 40 re-visiting patients with POP after vaginal
delivery 42 days were collected and then divided into a treatment group and a control group with 20 cases in each group. Patients in the
control group received pelvic floor muscle voluntary rehabilitation training, and the treatment group received pelvic floor muscle
voluntary rehabilitation training and electrical stimulation combined with biofeedback therapy. The morphological characteristics of
pelvic diaphragm hiatus, the perimeter and hiatus area of levator ani muscle were examined by transperineal three-dimensional
ultrasound under the state of resting, valsalva before treatment and after treatment, respectively. Results: The sizes of the levator ani
muscle hiatus were not much different between the control group and the treatment group before treatment, and the difference was not
statistically significant（P＞0.05）; the treatment group: the sizes of the hiatus after treatment were significantly different from those
before treatment（P＜0.05）; the control group: except for a statistically significant difference in the perimeters in the resting state
（P＜0.05）, there were no significant differences in the anteroposterior diameters and areas in the resting state, nor in the
anteroposterior diameters, the perimeters or the areas in the valsalva state（P＞0.05）before and after treatment; after treatment, the
treatment group and the control group showed no statistically significant difference in the anterior and posterior diameters in the resting
state（P＞0.05）. However, there were statistically significant differences in the perimeters and areas both in the resting and valsalva
state, and in the anterior and posterior diameters in the valsalva state（P＜0.05）. Conclusion: The application of transperineal
real-time three-dimensional pelvic floor ultrasound in the evaluation of postpartum female pelvic floor function and early postpartum
rehabilitation therapy is simple and feasible, and can provide a direct and objective imaging basis for clinical diagnosis.


Clinical Research of High-Frequency Ultrasound in Accurate Localization of ＜1 cm Breast Cancer and Precancerous Lesion

Xu Jiashun, Li Xiaodong, Yang Hua, Wang Wenlei

2020, 5(8):  62-64.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 014

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〔Abstract〕Objective: To investigate the clinical application of high-frequency ultrasound in accurate localization of ＜1 cm breast
cancers and precancerous lesions. Methods: With analyses of the sonographic features in 45 cases with ＜1 cm suspected small breast
lesions, their early diagnosis and pre-operation guide-wire localization in precise resection lesions, intraoperative findings and
pathological results were compared. Results: According to the position of the guide-wire, 45 suspicious small lesions of the breast were
accurately removed, and the accuracy rate of the first time insertion was 100%. Conclusion: For ＜1 cm breast cancers and precancerous
lesions, high-frequency ultrasound is helpful for early diagnosis, and pre-operation guide-wire positioning is helpful for early and
accurate resection of lesions.


Clinical and CT Analyses of 72 Cases of Neoplastic Lesions of Nasal Cavity and Paranasal Sinuses

Li Yanxian, Sang Jun, Li Zhenping, Bao Yujing, Ma Yumei, Li Xuemei

2020, 5(8):  65-69.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 015

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〔Abstract〕Objective: To analyze the clinical and CT findings of benign and malignant tumors of nasal sinus and to explore the
problems worthy of attention in diagnosis. Methods: A retrospective analysis of 72 cases（33 cases of benign and 39 cases of
malignant）clinical and CT data of patients with pathologically confirmed nasal cavity and sinus tumors was carried out, and the
clinical and imaging differences were compared. Results: There were significant differences in the age, nasal pain, nasal discomfort,
olfactory loss, and head and face pain between the two groups（P＜0.05）. There were significant differences in the density, boundary,
sclerotin between the two groups（P＜0.05）. The two groups were confined to the nasal cavity, the nasal cavity and sinus were involved,
invaded adjacent tissues, and the lymph nodes in the neck were compared. The difference was statistically significant（P＜0.05）. CT
diagnosis of benign tumors was misdiagnosed in 3 cases, the misdiagnosis rate was 9.09%; malignant tumors were misdiagnosed in 5
cases, and the misdiagnosis rate was 12.82%. Conclusion: The clinical symptoms of nasal sinus tumors are not typical, and CT can
make a more accurate qualitative diagnosis. For some cases that are difficult to identify, the diagnosis still relies on pathological
examination.


Clinical Diagnosis and Laboratory Analyses of 46 Cases of Infectious Mononucleosis

Xu Wenyan, Liu Qiuhong, Ouyang Yan

2020, 5(8):  70-73.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 016

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〔Abstract〕Objective: To investigate the clinical features of infectious mononucleosis（IM）, the characteristics of laboratory tests and
to provide help and reference for clinical diagnosis and treatment. Methods: This paper applied retrospective analysis, and collected
the clinical and laboratory data of 46 patients with IM in Yunnan kungang hospital from 2015 to 2018. The clinical characteristics of
IM patients and the characteristics of related laboratory indicators were studied. Results: The latest diagnosed patients were more
common with fever, lymphadenopathy and angina. Laboratory examination found that the total number of white blood cells, percentage
of lymphocytes, proportion of atypical lymphocytes and liver enzymes increased. The percentage of lymphocyte subsets CD8 + T cells
significantly increased, and CD4 + T cells significantly reduced, the differences were statistically significant（P<0.05）. CD8 + T cells
were not related to EBV - DNA load（P>0.05）, and CD4 + T cells were related to EBV-DNA load（P<0.05）. Conclusion: This paper
suggested that the symptoms are diverse when IM is onset, thus the laboratory tests have significant guiding importance for the initial
diagnosis of IM.


Epidemiological Characteristics of Elderly HIV/AIDS Patients Treated with HAART in Dali

Li Hongliu, Zhang Jianbo, Luo Hui, Zhou Xuying Han Tingting, Shen Yuanying

2020, 5(8):  74-78.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 017

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〔Abstract〕Objective: To understand the epidemiological characteristics of HIV/AIDS patients who accepted initial treatment aged
over 50 in Dali, and analyze the relevant characteristics of such patients, so as to provide scientific basis for the formulation of
prevention and control measures. Methods: The Comprehensive AIDS Prevention and Control Information System was used to collect
the case data of patients and describe the epidemic characteristics, including baseline data, treatment effec and loss of follow-up.
Results: From 2005 to 2018, 136 HIV/AIDS patients who accepted initial treatment aged over 50 were treated, including 92（67.65%）
males and 44（32.35%）females. The proportion of elderly patients in the whole age group increased year by year, reaching 12.99%
from January to June 2018. Sexual transmission was the main route of transmission with 126（92.65%）cases. Most of the patients were
Bai nationality with 88 cases（64.71%）. The antiviral effec of elderly HIV/AIDS patients was lower than that of non-elderly patients.
27 elderly HIV/AIDS patients died and they had a higher proportion of deaths from non-HIV/AIDS diseases which account for 59.26%.
The main transmission route of 17 elderly HIV/AIDS patients lost to follow-up was sexual transmission. Conclusion: For this special
population, the screening of elderly HIV/AIDS patients should be expanded and the follow-up work of elderly HIV/AIDS patients
should be carried out actively.


Analysis of Survival Time and Influencing Factors of HIV/AIDS Patients in Dali Prefecture from 1990 to 2015

Yang Lifen, Huang Lihua

2020, 5(8):  79-82.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 018

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〔Abstract〕Objective: To analyze the survival time and influencing factors of HIV/AIDS patients in Dali prefecture from 1990 to
2015. Methods: A retrospective cohort study was used to collect the relevant information of HIV/AIDS patients reported by Dali
prefecture from 1990 to 2015 in the Chinese Comprehensive AIDS Prevention and Control Information System. The survival probability
and median survival time were calculated by the life table method and Kaplan-Meier method, and the influencing factors of survival
time were analyzed by Cox proportional hazard regression model. Results: The median survival time of 8 760 HIV/AIDS patients was
12.75 years（95% CI: 12.08-13.75）. The results of Cox proportional hazard regression model analysis showed that the risks of death of
HIV/AIDS patients who were female, high school education or above, heterosexual sexually transmitted, for the first time of CD4 + T cell
count of 500/μL were 0.81 times, 0.84 times, 0.77 times and 0.26 times of those of the patients who were male, junior high school the
following cultural degree, injecting drug users spread, for the first time of CD4 + T cell count of <200/μL. The risks of death of the
patients aged ≥60 years at the diagnosis, diagnosed by medical institutions, and not receiving anti-retroviral therapy（ART）were 4.43
times, 1.52 times and 9.59 times of those of the patients aged 0-14 years, detection of consulting, and having received ART.
Conclusion: The median survival time of HIV/AIDS patients in Dali prefecture from 1990 to 2015 was 12.75 years. Female, high
school education and above, high CD4 + T lymphocyte count for the first time were protective factors for the survival of HIV/AIDS
patients. Older age, medical testing, and lack of ART were reported as risk factors for the survival of HIV/AIDS patients.


Analysis of Epidemic Situation on Registered Tuberculosis in Dali Prefecture from 2008 to 2017

Zhao Lina, Zhao Qingshan

2020, 5(8):  83-85.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 019

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〔Abstract〕Objective: To understand the features of tuberculosis epidemic in Dali prefecture, so as to provide scientific basis for the
prevention and control work. Methods: The epidemiological analysis of tuberculosis cases registered in the Tuberculosis Information
Management System of the Chinese Disease Prevention and Control Information System was carried out. The linear regression model of the
incidence rate was used to estimate the annual percentage change（APC）of the tuberculosis registration rate and smear positive registration
rate. Results: From 2008 to 2017, a total of 20 200 tuberculosis cases and 8 204 smear positive cases were registered in Dali prefecture.
The average annual tuberculosis registration rate and smear positive registration rate were 56.91/100 000 and 23.11/100 000, respectively;
The tuberculosis registration rate and smear positive registration rate decreased year by year, and the difference was statistically significant
（P＜0.05）. The APC were -2.873% and -10.860%, respectively. There were 13 606 male tuberculosis patients and 6 594 female
tuberculosis patients, the sex ratio of male to female was 2.06 ： 1; the young and middle-aged people were the majority; farmers and migrant
workers were the most with 18 088 cases, accounting for 89.54%. Conclusion: From 2008 to 2017, tuberculosis epidemic situation of Dali
prefectureshowedadownwardtrend,buttuberculosispreventionandcontrolworkstillneedstobestrengthened.


Analysis on the Epidemiological Characteristics of Ascaris in Primary School Students in Five Monitoring Years from 1991 to 2014 in Dali Prefecture

Liu Yanjun, Guan Fang

2020, 5(8):  86-88.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 020

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〔Abstract〕Objective: To explore the epidemiological characteristics of ascaris in primary school students in Dali prefecture from
1991 to 2014, and provide reference for the next step of prevention and control strategy. Methods: According to the requirements of the
National Handbook of Investigation and Research on Students' Physical Health, statistics and analysis were conducted on ascaris
infection rates among Dali primary school students in 1991, 2000, 2005, 2010 and 2014 respectively. Results: In the five monitoring
years from 1991 to 2014, the infection rate of ascaris in primary school students was the lowest in 2000, which increased slightly in 2005
and then decreased continuously, and then decreased to 6.17% in 2014. Compared with Bai nationality, Han nationality was lower than
Bai nationality in 1991, 2000 and 2005, with statistically significant differences（ χ 2 =4.84, 4.55 and 13.86, P<0.05）, while there were no
statistically significant differences in 2010 and 2014（ χ 2 =1.63, 0.53, P>0.05）. In each monitoring year, there was no statistically
significant difference between boys and girls（P>0.05）. Conclusion: The infection rate of ascaris is at a low level among primary school
students in Dali prefecture, and the possibility of rebound is small. The prevention and treatment work in the future should focus on
health education.


Research on the Effect of Nursing Intervention of Patient Controlled Epidural Analgesia after Electric Resection of Prostatic Hyperplasia in 76 Cases

Wang Yahong, Yang Yi

2020, 5(8):  89-92.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 021

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〔Abstract〕Objective: To explore the effect of nursing intervention of patient controlled epidural analgesia after electric resection of
prostatic hyperplasia. Methods: 76 patients undergoing electric resection of prostatic hyperplasia in the department of Urology of The
First Affiliated Hospital of Dali University from August 2017 to December 2018 were selected as subjects. According to the sequence of
operation time, they were divided into the control group（regular nursing group）and the experimental group（nursing intervention
group）with 38 cases respectively. The degree of satisfaction with analgesia and the incidence of postoperative adverse reactions to the
use of patient controlled epidural analgesia（PCEA）were compared between the two groups. Results: After targeted comprehensive and
meticulous nursing care, the satisfaction degree of analgesic pump in the experimental group was higher than that in the control group,
and the incidence of analgesic adverse reactions was lower than that in the control group, the differences were statistically significant（P
< 0.05）. Conclusion: Providing comprehensive and meticulous nursing intervention in the process of epidural analgesia for patients
after electric resection of prostatic hyperplasia can improve patients' satisfaction with the analgesia effect, and also reduce the incidence
of adverse reactions of epidural analgesia, so that patients can better survive the postoperative pain and recover as soon as possible.


Application of Juran Quality Trilogy in Hospital Quality Control Circle

Yang Taoxian, Li Wei, Wang Tao, Zhao Min

2020, 5(8):  93-96.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 022

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〔Abstract〕Objective: To explore the application of Juran quality trilogy in hospital quality control circle. Methods: The hospital
established a quality control circle implementation leading group, and applied the Juran quality trilogy to manage the entire process of
quality control circle. Existing problems and deficiencies were analyzed and improvements were made. Results: The quality control
circle was piloted and carried out in the hospital, and the scope of improvement involves medical treatment, nursing, pharmacy, medical
technology, administration and logistics, forming a long-term mechanism for quality improvement. Conclusion: The introduction of
Juran quality trilogy into the implementation of hospital quality control circle, and the initiation of project improvement by means of
"planning, control and improvement", can better regulate management behavior, optimize management mode, and provide a strong
guarantee for the implementation of quality control circle.


Study on the Effect of Role-Play on the Hazard Prediction Training for Nursing Students

Rao Yanhua, Quan Yuan, Wu Xingjun

2020, 5(8):  97-100.  DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 08. 023

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〔Abstract〕Objective: To explore the comparative effect of role-playing method and illustration method in hazard prediction training
for nursing students. Methods: 96 sophomore nursing students in the class of 2017 in a college were randomly selected and divided
into role-play group and illustrations group. Participants were asked to complete the risk sensitivity scale for nursing students before
and after training. After training, all participants were asked to take a hazard prediction test. The mixed linear model was used for
statistical analysis on the results. Results: The risk prediction score of the role-play group was significantly higher than that of the
illustrations group（role-play group（2.89±1.36）vs. illustrations group（1.41±1.44）, and the difference was statistically significant
（P＜0.05））. After training, the scores of risk sensitivity scale of nursing students in both groups were significantly improved, but the
difference was not statistically significant（P＞0.05）. Conclusion: Role-play can enable nursing students to put forward more risk
points in the hazard prediction training, but both role-playing method and illustration method can improve the risk sensitivity of
nursing students. Therefore, it can be selected in the teaching according to the specific situation, and further exploration and research
are needed.