Journal of Dali University

Reflections on the Effective Governance Strategies of Public Health Emergencies:#br# A Case Study of COVID-19

Si Junxiao

2020, 5(10): 1-7. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 001

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〔Abstract〕Objective: The current situation and problems of COVID-19 prevention and control are analyzed and sorted out, so as to
provide reference for the construction of rapid response mechanism for public health emergencies. Methods: The epidemic data were
collected from the official website of the National Health Commission, and descriptive statistics were carried out according to three
dimensions: confirmed and suspected, the whole country/Hubei, and the areas outside Hubei. Results: In the early stage of epidemic
prevention and control, the strategy was mainly to prevent the coronavirus from spreading within the country, and in the later stage, the
strategy changed into preventions of input. The prevention and control of the epidemic has roughly gone through four stages, i.e. the
incubation period, the outbreak period, the plateau period and the regression period. In the process of epidemic prevention and control,
problems such as unrealistic work style, inadequate coping capacity, lack of emergency support, and fluke psychology have emerged.
The root causes of the problems include structural factors, environmental factors, institutional factors and social factors. Only by
adhering to four principles and implementing normalized management in terms of legal protection, digital governance and social capital
can we achieve effective management of public health emergencies. Conclusion: The solution to public health emergencies should
change from abnormal management to normal management.

Epidemiological Analysis of COVID-19 Epidemic in Ganzi Tibetan Autonomous Prefecture of#br# Sichuan Province

Yin Chunlei, Li Lijuan

2020, 5(10): 8-10. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 002

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〔Abstract〕Objective: To understand the epidemic characteristics of COVID-19 in the Ganzi Tibetan Autonomous Prefecture of
Sichuan Province in 2020, and to provide a theoretical basis for prevention and treatment. Methods: The descriptive epidemiological
method was used to analyze the epidemic characteristics of COVID-19 in Ganzi Tibetan Autonomous Prefecture. Results: As of
February 27, a total of 78 confirmed cases of COVID-19 were reported in Ganzi Tibetan Autonomous Prefecture of Sichuan Province.
The first case was reported on January 25, and since February 9, there had been new cases every day for 13 consecutive days. Of all the
reported cases in the autonomous prefecture, among which 5 cases were imported from Wuhan, and 73 cases were natives of Daofu
county in Ganzi Tibetan Autonomous Prefecture. The cases were mainly young and middle-aged, and the male-female sex ratio was
1.23：1. Conclusion: The COVID-19 control in Ganzi Tibetan Autonomous Prefecture of Sichuan Province is going on well, but the
prevention and control still need to be strengthened, and the investment in medical and health care should be increased in the future.

Novel Coronavirus Infection in Children: A Report of Clinical Characteristics of Four Cases in Kunming

Zhang Le, Zhang Kaiyi, Ma Zhongxu, Li Yunzhen, Qi Fei, Xia Jiawei

2020, 5(10): 11-15. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 003

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〔Abstract〕Objective: To investigate the clinical characteristics of novel coronavirus infection in children. Methods: The clinical
data of four children confirmed with novel coronavirus infection in Kunming were retrospectively analyzed, and the clinical
characteristics of the children were analyzed and summarized. Results: All the four cases had clear epidemiological histories, including
three cases of fever, three cases of cough, one case of sore throat, and one case of asymptomatic and insidious onset. The lymphocyte
numbers were normal, but the absolute value of white blood cells, CD3+, CD4+ and CD8+ significantly decreased in a very young child,
and CD4+T lymphocyte slightly decreased in two children. There was one case of atypical abnormal changes in chest imaging, and three
children had no abnormalities in chest imaging. The clinical symptoms of the children were alleviated by antiviral therapy combined
with Chinese medicine decoction. For two cases, the fecal nucleic acid of the new coronavirus was tested positive for many times, and
the negative rotation time of the pharyngeal swab and the fecal nucleic acid was not synchronized, the latter was later than the former.
Conclusion: Close family contact is the main route of transmission of novel coronavirus for children, and other means of transmission
also need to be alerted. Children cases are mainly mild and recessive, and the harm as a source of respiratory infection may be limited.
However, some cases of fecal virus nucleic acid turned negative later than the swab, so it is necessary to guard against fecal-oral
transmission which may become the blind spot of infection source management.

Analysis of Epidemiological Characteristics of COVID-19 Cases in Dali Bai Autonomous Prefecture

Ding Likun

2020, 5(10): 16-19. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 004

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〔Abstract〕Objective: To understand the epidemic process and characteristics of COVID-19 in Dali Prefecture, and to provide basis
for formulating prevention and treatment measures. Methods: The epidemiological data of 13 cases of COVID-19 diagnosed in Dali
Prefecture from January 24 to February 9, 2020 were collected and retrospectively analyzed. Results: The average age of 13 confirmed
cases was 41.8 years old; the average interval between onset and diagnosis was 4.8 days; a total of diagnosis cases were common and
mild infections; there was no death; except for 2 local cases, the rest were all imported; 6 confirmed cases were infected in 2 clusters,
accounting for half of the imported cases. Conclusion: The prevention and control measures taken by Dali Prefecture in response to the
COVID-19 epidemic had been effective, and there was no spread of the epidemic or community transmission.

Ordinary COVID-19 Associated with HIV Infection: A Case Report and Literature Analysis

Wang Ji, Bin Songtao, Li Ming, Tan Li

2020, 5(10): 20-23. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 005

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〔Abstract〕Objective: To analyze the clinical characteristics of a patient with common COVID-19 associated with HIV infection.
Methods: The clinical data of a patient with COVID-19 and HIV infection admitted to the Chibi People's Hospital was analyzed, and
the characteristics and treatment of the disease were analyzed combining literature. Results: There was no obvious respiratory
symptoms on the patient. Blood routine examination showed normal or decreased total white blood cell count, decreased lymphocyte
count. There were no specific changes in C-reactive protein. CD4+ and CD8+ in lymphocyte subsets were normal. The chest CT of the
patient showed multiple patchy ground glass shadows, increasing light patchy density shadows, and blurred edges, especially in
external bands. After anti-infection treatment, the patient was discharged after 18 days in hospital. Conclusion: The clinical
manifestations of this case of common COVID-19 associated with HIV infection with normal level of CD4+ T are similar to that of
common COVID-19. The first choice for treatment is anti-aids drugs, which can achieve good results.

Review and Analysis of 36 000 Outpatient Prescriptions from 18 County Hospitals in Qujing City

Guo Jianwei, Huang Xingfu, Yu Mei, Yang Yuxian, Ma Li, Fa Yanmei

2020, 5(10): 24-28. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 006

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〔Abstract〕Objective: To investigate the situation of outpatient prescription in 18 county hospitals in Qujing City, and evaluate the
current situation of outpatient prescription drug use in county hospitals in Qujing City, so as to provide reference for promoting rational
drug use. Methods: Retrospective review and analysis were conducted on 36 000 outpatient prescriptions randomly selected from 18
county hospitals in Qujing City in 2019. Results: The average number of drug categories used in outpatient prescriptions of 18 county
hospitals was 2.69, the average cost of a single prescription was 63.15 yuan, the utilization rate of injection was 33.00%, the utilization
rate of antibiotics was 16.44%, the combined utilization rate of antibiotics was 3.97%, the utilization rate of basic drugs was 59.66%, the
utilization rate of glucocorticoids was 10.06%, and the qualified rate of prescription was 90.11%. Among the unreasonable prescriptions,
28.27% were irregular prescriptions, 58.96% were unsuitable prescriptions, and 12.77% were abnormal prescriptions. Conclusion: By
commenting on the outpatient prescription of 18 county hospitals, the level of outpatient prescription and the current situation of rational
drug use in Qujing county hospitals are preliminarily grasped, which provides data reference for further improving the outpatient
prescription rationality rate and strengthening the prescription management of county medical institutions.

A Meta-Analysis of Efficacy and Safety of Kangfuxin Liquid in the Treatment of Complex Wound Injuries

Ou Ling, Yang Lianzhu, Peng Fang

2020, 5(10): 29-34. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 007

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〔Abstract〕Objective: To systematically evaluate the efficacy and safety of Kangfuxin Liquid in the treatment of complex wound
injuries. Methods: PubMed, the Cochrane Library, CNKI, VIP and Wanfang databases were searched for eligible studies. The contents
were limited to randomized controlled trials of Kangfuxin Liquid in the treatment of complex wound injuries. The quality of the included
literature was evaluated, and relevant data were extracted. The RevMan 5.3 software was used for Meta-analysis of the data. Results: A
total of 7 clinical studies involving 531 patients were included. The main outcome indicators were the total effectiveness of Kangfuxin
solution in treating wounds, wound healing time, and VAS score. Meta-analysis showed the total effective rate of Kangfuxin Liquid in
treating complex wounds was higher than that in the control group［OR =5.63, 95%CI（2.89, 10.97）, P <0.001］, wound healing time
was shorter than the control group［MD=-4.83, 95%CI（-8.43, -1.22）, P <0.05］and patients had less pain than the control group
［MD=-0.91, 95%CI（-1.24, -0.58）, P<0.001］. Conclusion: The research shows that compared with conventional common dressings,
Kangfuxin Liquid was more effective in treating wound injuries, with shorter wound healing time and less pain of the patients. All the
differences were statistically significant, and basically had no adverse reactions. It has good effectiveness and safety, but more highquality
studies are still needed to guide its clinical rational drug use.

Effects of Mycobacterium tuberculosis with Different Virulence on the Apoptosis Rate of Mouse Dendritic Cells

Li Ping, Li Congzhe, Wu Lixian

2020, 5(10): 35-39. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 008

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〔Abstract〕Objective: To study the effects of Mycobacterium tuberculosis（Mtb）with different virulence on the apoptosis rate of mouse
dendritic cells（DC）2.4. Methods: The mixed cell culture models of mouse DC2.4 infected with Mtb standard strain H37Ra and Mtb
clinically isolated 14-11 were established respectively. The apoptosis of DC2.4 was detected by Annexin V-FITC/PI fluorescence
labeling flow cytometry at 1, 3, 6, 12 and 24 h after infection, and the phasic changes were analyzed. Results: Both the strains of
H37Ra and 14-11 could induce the apoptosis of DC 2.4, and it was obvious that the apoptosis rate increased at 12 hours after infection.
There was no significant difference between the two groups in the apoptosis rate（P > 0.05）. The apoptosis rate of DC2.4 in mice
induced by 14-11 was lower than that induced by H37Ra at all time points after induction, and the apoptosis rate increased
significantly after induction for 12 h. Conclusion: Mtb with different virulence can induce apoptosis quickly after infecting DC2.4 in
mice. The apoptosis rate may be related to the different virulence of the induced strain. Compared with the clinically isolated 14-11,
H37Ra standard strain of weaker virulence induced higher rate of apoptosis.

Expression and Significance of the TOP2A Gene in Pancreas Cancer: An Analysis Based on Data Mining

Mei Wen, Sun Ruli, Li Yun, Xiong Wei, Zhao Yi

2020, 5(10): 40-47. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 009

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〔Abstract〕Objective: To explore the expression of topoisomerase Ⅱ alpha（TOP2A）and its prognostic role in pancreas cancer.
Methods: Data about TOP2A were retrieved from the database and the role of TOP2A in pancreas cancer was analyzed. Results: The
mRNA expression of TOP2A in pancreas cancer was significantly higher than that in normal pancreatic tissue. Patients with higher
mRNA expression tended to have a significantly poorer prognosis（P<0.05）than those who had lower mRNA expression, but the
expression levels of TOP2A were not related to pathological stage of pancreatic cancer patients（P>0.05）. The methylation level of
TOP2A promoter region in pancreatic cancer has no difference with normal pancreatic tissue（P>0.05）. The genes interacting with
TOP2A included CDK1, HDAC1, NFE2L3 and so on. The proteins interacting with TOP2A included CDK1, CDC20, TOP1 and so on.
Conclusion: TOP2A is highly expressed in pancreatic cancer tissues, and its expression level is significantly related to the prognosis of
pancreatic cancer. The interaction of TOP2A and other genes may jointly participate in the occurrence and development of pancreatic
cancer.

Two Cases Report of HFRS Complicated with AP and Literature Review

Huang Lihua, Luo Jiao, Li Quanrun, Gu Wei

2020, 5(10): 48-50. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 010

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〔Abstract〕Objective: To understand the hemorrhagic fever with renal syndrome（HFRS）complicated with acute pancreatitis（AP）.
Methods: The diagnosis and treatment of 2 cases of HFRS complicated with AP were reported, and the possible pathogenesis, clinical
features, diagnosis, treatment and prognostic factors were analyzed. Results: The 2 patients have fever, backache, abdominal pain,
bleeding specific antibody IgG and IgM positive, blood amylase elevated, and abdominal CT were considered HFRS complicated with
AP; one patient died of multiple organ failure due to invasive ventilator-assisted respiration and bedside continuous hemofiltration
treatment; the other case was transferred to a superior hospital, but had multiple organ dysfunction one week later, and the family
members decided to give up. 15 literatures at home and abroad were searched, including 39 cases of HFRS complicated with AP, 37
cases（94.9%）had no contact history of infectious source, 3 cases（7.7%）were misdiagnosed, and 5 cases（12.8%）were treated with
bedside continuous hemofiltration. HFRS can also complicated with other diseases, including pulmonary edema, rhabdomyolysis, etc.
Conclusion: HFRS complicated with AP is rare. Clinical features, laboratory examination and abdominal CT are very important for
diagnosis. To improve the understanding of the disease, early diagnosis and early treatment is the key to reduce mortality.

Effects of "Psycho-Cardiology Medical Mode" on Patients of Resistant Hypertension with#br# Anxiety and Depression

Chen Tianyu, Sun Zhen, Li Zixuan

2020, 5(10): 51-54. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 011

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〔Abstract〕Objective: To explore the effects of "psycho-cardiology medical mode" on patients with resistant hypertension and
anxiety and depression. Methods: 80 patients of resistant hypertension with anxiety and depression diagnosed and admitted from
March 2019 to June 2019 in the Eighth People's Hospital of Hefei were divided into a control group and an observation group
according to the principle of random grouping, with 40 cases in each group. The control group was treated with conventional therapy,
and the treatment group was treated with "psycho-cardiology medical mode" on the basis of conventional therapy. After one month of
treatment, the two groups were compared in blood pressures, SAS scores and SDS scores. Results: The effect of lower blood pressures
in the treatment group was better than that in the control group, and the difference was statistically significant（P < 0.05）; the scores
of SAS and SDS in the treatment group were lower than those in the control group, and the differences were statistically significant
（P < 0.05）. Conclusion: "Psycho-cardiology medical mode" can significantly relieve the blood pressure, anxiety and depression of
patients with resistant hypertension, and has certain clinical value.

A Comparison of Clinical Efficacy between Minimally Invasive and Open TLIF in the Treatment of Single-Segment Lumbar Spinal Stenosis

Wang Shiyong, Yao Rubin, Yang Kaishun

2020, 5(10): 55-63. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 012

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〔Abstract〕Objective: To evaluate the clinical effect of MIS-TLIF in the treatment of single-segment lumbar spinal stenosis.
Methods: The clinical data of patients with single-segmental lumbar spinal stenosis treated by MIS-TLIF and Open-TLIF in the
department of spinal surgery of the First Affiliated Hospital of Dali University from January 2015 to January 2017 were selected.
Among them, 39 patients underwent MIS-TLIF operation（MIS-TLIF group）and 46 patients underwent Open-TLIF operation（Open-
TLIF group）. The follow-up period was up to November 2018. The operation time, the number of intraoperative C-arm fluoroscopy,
intraoperative blood loss, postoperative drainage, total hospitalization time, postoperative hospitalization time, total hospitalization cost
and postoperative adverse events were recorded, and the curative effect was evaluated according to VAS and ODI scores. The failure of
internal fixation was recorded, and lumbar CT reconstruction scan was performed to evaluate the fusion of surgical segments at the last
follow-up. Results: There was no significant difference in the general condition between the two groups（P > 0.05）. The length of
operations, the times of fluoroscopy and the total costs of hospitalization in MIS-TLIF group were significantly higher than those in
Open-TLIF group, and the differences were statistically significant（P<0.05）; the postoperative drainages, postoperative hospital stays
and the last ODI scores in MIS-TLIF group were significantly lower than those in Open-TLIF group, and the differences were statistically
significant（P<0.05）. In Open-TLIF group, two cases underwent secondary operation（1 case of incision infection and 1 case of screw
misplacement）, and 1 case in MIS-TLIF group underwent revision operation because of Cage displacement and loosening of internal
fixation. Conclusion: For single-segment lumbar spinal stenosis, MIS-TLIF has the same effect as Open-TLIF in improving clinical
symptoms and fusion rate, and does not increase perioperative adverse events, so it is a safe and effective interbody fusion.

Application of Individualized Puncture Path in PVP/PKP with Unilateral Puncture

Bai Tao, Zhao Hui, Liang Jin, Dong Xie, Wang Guozhu, Na Qiang

2020, 5(10): 64-68. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 013

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〔Abstract〕Objective: To discuss the clinical effect of individualized puncture path in PVP or PKP with unilateral puncture.
Methods: 97 patients with osteoporotic vertebral compression fractures（OVCF）who underwent PVP or PKP surgery with unilateral
puncture were selected as the research objects, and the puncture technique implemented according to the preoperative individualized
puncture route was described so as to observe the puncture results, bone cement dispersion and evaluate postoperative efficacy.
Results: The 97 patients were successfully punctured according to the preoperative individualized design. The 97 postoperative VAS
score, ODI score, and Cobb angle were significantly improved compared with preoperatively. The differences were statistically
significant（P<0.05）. There was no statistically significant difference in indicators in the next 3 months（P>0.05）. Conclusion: Good
placement of working cannula is the premise of satisfactory of diffusion of bone cement, and the application of individualized puncture
path can acquire good placement of working cannula.

Therapeutic Observation of Warm Needling Combined with Pelvic Floor Muscle Training for Urinary Incontinence after Stroke

Qiu Meihua

2020, 5(10): 69-71. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 014

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〔Abstract〕Objective: To observe the clinical efficacy of warming acupuncture combined with pelvic floor exercise in the treatment of
stroke urinary incontinence. Methods: 109 patients with urinary incontinence who were hospitalized in the Second People'S Hospital
of Yunnan Province from March 2015 to March 2018 were randomly divided into a treatment group（55 cases）and a control group（54
cases）. The treatment group was treated with warming acupuncture and pelvic floor exercise, while the control group was given pelvic
floor exercise only. Curative effect was evaluated after two courses of treatment. Results: The effective rate of the treatment group
was 85.45%, which was better than that of the control group（68.52%）, and the difference was statistically significant（P<0.05）.
Conclusion: Warming acupuncture combined with pelvic floor exercise can improve the innervation of bladder sphincter and inhibit
the non-inhibitory contraction of detrusor, which can relieve urinary incontinence.

Two Cases of Acute Poisoning of Blaps rynchopetera Fairmaire

Zhou Rong, Shi Biao, Yang Canju, Wang Lei, Yang Limin, Zhao Zhonghua

2020, 5(10): 72-74. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 015

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〔Abstract〕Objective: To investigate the diagnosis and treatment of Blaps rynchopetera Fairmaire poisoning. Methods: The clinical
data of two poisoning patients were retrospectively analyzed. Results: Two elderly patients were involved in this study. One died of
ventricular tachycardia. Another was cured after systemic comprehensive treatment. Conclusion: Blaps rynchopetera Fairmaire can
result in poisoning. The patients show fatal ventricular arrhythmia and hypoxemia pressure shock. At the early stage, the patients may
experience limb anesthesia which is easy to misdiagnosed. Thus, dynamic of electrocardiogram and blood pressure fluctuation need to
be evaluated.

The Value of Serum AFP, B7-H4 Combined with CP Detection in the Diagnosis of Primary Hepatic Carcinoma

Yang Gaibiao, Li Qian, Li Xuan, Gong Nianting, Zhang Shengmei

2020, 5(10): 75-79. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 016

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〔Abstract〕Objective: To explore the diagnostic value of serum alpha-fetoprotein（AFP）, co-stimulatory molecule B7-H4 combined
with ceruloplasmin（CP）for primary hepatic carcinoma（PHC）. Methods: Forty-two PHC patients who were treated in the 32268
Troop of People's Liberation Army during the period from September 2017 to September 2018 were selected as the PHC group, 60
patients with benign liver disease were selected as the benign liver disease group, and another 60 healthy controls during the same
period were selected as the control group. The fasting venous blood in each subject was collected to separate serum. The contents of
serum AFP and B7-H4 were detected by electrochemiluminescence method. The content of serum CP was detected by immunity
transmission turbidity. The levels of serum AFP, B7-H4 and CP were compared among all groups. The diagnostic value of serum AFP,
B7-H4, CP and their combination for PHC was explored. Results: The contents of serum AFP, B7-H4 and CP in the PHC group were
significantly higher than those in the benign liver disease group and the control group（P<0.05）. The area under the ROC curve
（AUC）values of serum AFP, B7-H4 and CP for diagnosis of PHC were 0.712, 0.816 and 0.754, and their corresponding cut-off values
were 103.78 μg/L, 50.39 ng/mL and 0.31 g/L, respectively. AUC of their combination detection was 0.897, which was significantly
higher than that of single index（P<0.05）. The sensitivity, specificity and accuracy of serum AFP combined with B7-H4 and CP
detection were 92.86%, 93.33% and 93.21%, which were higher than those of single index. Conclusion: The combination detection of
serum AFP, B7-H4 and CP can significantly improve diagnosis rate of PHC, which is of great significance for clinical diagnosis of PHC.

Analysis on the Survival Status of HIV/AIDS Patients in Dali City

Chen Xiaoming, Huang Lihua

2020, 5(10): 80-83. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 017

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〔Abstract〕Objective: The survival time and influencing factors of HIV/AIDS patients in Dali city from 1990 to 2018 were analyzed
to provide scientific basis for better prevention and treatment of AIDS. Methods: A retrospective cohort study was conducted to analyze
HIV/AIDS patients in Dali city from 1990 to 2018. The survival rate was calculated by life table, and Cox proportion hazard regression
model was used to analyze the influence factors of the HIV/AIDS patients' survival time. Results: The cumulative survival rates of sub?
jects 1, 5, 10, 15 and 20 years were 86.22%, 73.98%, 63.26%, 48.90% and 43.51%, respectively. Cox proportion hazard regression
model analysis results showed that male, drug injection, no antiviral treatment, and low CD4+ T lymphocytes level at the first check were
risk factors affecting the survival time of patients. The risk of death for HIV/AIDS patients from 2006 to 2010 and after 2010 was 0.72
times（95% CI: 0.64 to 0.82）and 0.69 times（95% CI: 0.49 to 0.97）compared to that of before 2006. Conclusion: Early detection and
early antiviral treatment can effectively reduce the risk of death of HIV/AIDS patients.

Thoughts on the Construction of Teaching Experiment Platform for Emergency Treatment of Public Health Emergencies

Sui Shiyan, Guo Lijun, Cao Liang, Song Zhengrui, He Zuoshun

2020, 5(10): 84-87. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 018

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〔Abstract〕Objective: To improve the theoretical level and emergency handling ability of public health and preventive medicine
undergraduates in dealing with public health emergencies. Methods: On the basis of the original experimental teaching center of
College of Public Health in Dali University, the characteristic virtual simulation practice course is designed carefully by strengthening
the condition construction of virtual simulation teaching platform. Results: A virtual simulation experiment teaching platform and
experimental training center for public health professional skills have been built as well as a virtual simulation practice teaching system
with wide coverage and complete functions. Conclusion: The teaching experimental platform for emergency treatment of public health
emergencies combines online virtual reality teaching with offline physical teaching, which has effectively improved the educational and
teaching effects.

Evidence-Based Nursing Practice of Routine Maintenance of Multi-Center Adult Short-Term Indwelling Catheter

Yang Chunfang, Yang Yanfen, Zhang Li, Ren Tianguang, Luan Yuquan, Fu Yanfen

2020, 5(10): 88-92. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 019

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〔Abstract〕Objective: To apply the best evidences of routine maintenance of adult short-term indwelling catheters to clinical
practices, carry out evidence-based nursing practice, and promote continuous improvement of clinical nursing. Methods: Search the
database to obtain the latest and best evidences for the routine maintenance of adult short-term indwelling catheters and form
recommendations, formulate operational procedures and standards, train nursing staff, design patients' data sheets and questionnaires
for observation and investigation, and finally evaluate nurses' work efficiency with patients' comfort levels, related medical expenses,
and nurses' knowledge of evidences. Results: After the application of the best evidences, the urinary tract infection rate was not
statistically significant（P>0.05）. The patients had higher comfort levels and lower costs, and the nurses had better work efficiency and
improved knowledge and use of evidences. The differences were statistically significant（P<0.05）. Conclusion: The best evidences for
routine maintenance of short-term indwelling catheters for clinical practices have no statistically significant effects on urinary tract
infections（P>0.05）, but it can improve patients' comfort, reduce patient medical expenses, improve the work efficiency of nurses and
the awareness and implementation rate of evidence application, and therefore improve the quality of care.

Research on Teaching Methods of Clinical Practice in Critical Care of Infectious Diseases

Liu Li, Qian Liyun, Huang Hongli, Zhang Qiang, Shi Aiyun, Li Haiwen

2020, 5(10): 93-96. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 020

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〔Abstract〕Objective: To observe the effects of mini-clinical evaluation exercise（Mini-CEX）combined with scenario simulation in
clinical practice teaching of critical care of infectious diseases. Methods: 160 nursing students were randomly divided into a control
group and an experimental group by using random number table, with 80 students in each group. The control group adopted traditional
teaching method, while the experimental group adopted Mini-CEX combined with scenario simulation teaching method on the basis of
the control group. At the end of the internship, the evaluation results of clinical comprehensive ability of critical care of infectious
diseases were compared between the two groups of nursing students, as well as the four dimensions satisfaction of doctors, nurses,
patients and nursing students. Results: The evaluation results of clinical comprehensive ability showed that the experimental group had
higher scores in communication ability, problem solving ability, clinical operation ability, flexible application of theoretical knowledge,
clinical cooperation ability and humanistic care ability than the control group, the total score of the experimental group was also higher
than that of the control group, and the differences were statistically significant（P<0.05）. The satisfaction evaluation results showed
that in the experimental group, the scores of nurses' satisfaction with nursing students and nursing students' satisfaction with teaching
were higher than those in the control group, and the differences were statistically significant（P<0.05）. Conclusion: Mini-CEX
combined with scenario simulation teaching can effectively improve the clinical comprehensive ability of the nursing students and
improve satisfaction degree, and can be popularized in the clinical practice teaching of the critical care of the infectious diseases.

Reform and Practice of College English Courses for Nursing Major in Frontier Colleges:#br# Tourism and Culture College of Yunnan University as an Example

Qian Jinfu, Ge Xiaowu, Tao Aien, He Shiqiong

2020, 5(10): 97-100. DOI: ［DOI］10. 3969 / j. issn. 2096-2266. 2020. 10. 021

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〔Abstract〕Objective: To solve the problem that College English takes up too many credits and change the situation that many
students don't like English study and can't study well, so students can study some more useful courses in College English time.
Methods: College English is changed into non-compulsory courses, credits were compressed, and a new course structure and contents
were constructed. In the second year, students are free to choose from College English, Nursing English and Chinese Sign Language
based on their own will. Results: Students' initiative in learning language had been improved evidently, and the number of students
who failed their examination had decreased drastically. This has basically changed the situation that students don't like College English
and their specialty English has been improved accordingly. The students with lowest English achievements were able to acquire the
ability to communicate with handicapped person by taking Chinese Sign Language electively. Conclusion: This reform is widely
welcomed by nursing students, and some peer experts supported this reform, so did some primary hospitals. This reform has achieved
its expected goals.

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